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Drug description

Active ingredient and dosage form

Diazolin tablets, tablets
1 pill contains mebhydrolin 50 or 100 mg;
10 or 20 pcs. packaged.

Mechanism of action

Diazolin - histamine H blocker1-receptors.
It has anti-allergic, antipruritic, anti-exudative, as well as a weak sedative effect. Blocks histamine H1 receptors, lowers the tone of smooth muscles (bronchi, gastrointestinal tract, uterus), reduces capillary permeability and the development of edema, prevents the occurrence of itching.

Indications and usage

Allergic rhinitis (seasonal, chronic), pollinosis, allergic conjunctivitis, urticaria, angioedema, pruritic dermatosis (eczema, neurodermatitis, etc.), skin reaction to insect bites; allergic reactions to medication, food, etc.; combination therapy of pruritic dermatosis and bronchial asthma.


Prostatic hypertrophy, angle-closure glaucoma, gastric ulcer and duodenal ulcer, inflammatory diseases of the gastrointestinal tract in the acute phase; Hypersensitivity to mebhydroline, children under 2 years old.

Restrictions on the use of: 

Pyloric stenosis, epilepsy, cardiac arrhythmia.

Dosage and administration

Diazolin is prescribed inside after eating.
For adults andchildren over 10 years old: 50-300 mg per day. The maximum single dose - 300 mg daily - 600 mg.
Children 5-10 years old: 100-200 mg per day.
Children 2-5 years: 50-150 mg per day.

Adverse reactions

From the nervous system and sensory organs: fatigue, slow reaction rate, dizziness, drowsiness, paresthesia.
On the part of the digestive tract: dry mouth, heartburn, nausea, epigastric pain.
Other: violation of urination, allergic reactions, granulocytopenia, agranulocytosis.

Special notes

Be wary appointed during pregnancy and lactation.
Caution is also needed when using against the background of liver and kidney diseases (dose adjustment and intervals between doses are possible).
With caution, the drug is prescribed to patients engaged in potentially hazardous activities that require increased attention and quick psychomotor reactions.

Drug interactions

Diazolin enhances the effect of CNS depressants.

Storage conditions

In dry, the dark place at a temperature below 25 ° C

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