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HISTAFEN PILLS 50MG 20 tablets



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Active ingredient: sehifenadine hydrochloride dihydrat 50 mg;

Excipients: lactose monohydrate - 302 mg; MCC - 20 mg; corn starch - 20 mg; silicon dioxide - 2 mg; Magnesium stearate - 6 mg

Indications and usage

  • allergic rhinitis;
  • allergic conjunctivitis;
  • pollinosis;
  • hives;
  • angioedema;
  • allergic pruritic dermatosis, incl. atopic dermatitis;
  • prevention of diseases of an allergic nature to the period of their seasonal exacerbation and supportive therapy.


  • hypersensitivity to the active substance or excipients of the drug;
  • bronchial asthma;
  • pregnancy;
  • lactation period;
  • children up to 18 years;
  • simultaneous administration of MAO inhibitors.

The composition of the pill includes lactose. The drug should not be used in case of lactase deficiency, rare hereditary lactose intolerance or glucose / galactose malabsorption.

With care: at violations of functions of kidneys, serious diseases of SSS, a gastrointestinal tract, a liver.

Adverse reactions

Dry mouth, epigastric pain, dyspepsia, increased appetite, leukopenia, menstrual disorders, increased urination, headache, drowsiness. Excitement, insomnia, which are more common when taking high doses.

Drug interactions

Sehifenadine does not enhance the inhibitory effect on the central nervous system of hypnotic drugs and alcohol, but during treatment it is necessary to refrain from drinking alcohol.

Inside, after eating, drinking water. Adults with acute and chronic allergic diseases - 50-100 mg 2-3 times a day. Usually, the therapeutic effect occurs 3 days after the start of treatment. Duration of treatment is 5-15 days.

Prevention of allergic diseases before the period of their seasonal exacerbation and for maintenance therapy - 50 mg 2 times a day. Taking the drug is recommended to start 2 weeks before the expected impact of the seasonal allergen.


Symptoms: dry mucous membranes, headache, vomiting, abdominal pain.

Treatment: symptomatic therapy. The antidote is unknown.

Special notes

There are no clinical studies on the use of the drug in children and patients of senile (after 70 years) age.

Sehifenadine pills can be combined with topical preparations (ointment, eye drops, nasal drops).

In most cases, drowsiness decreases or disappears 2-5 days after the start of treatment.

Influence on the ability to drive a car or perform work that requires increased speed of physical and mental reactions. Persons whose work requires a quick physical or mental reaction (drivers of vehicles, etc.) must refrain from driving and engaging in potentially hazardous activities during the period of treatment.

Storage conditions

In dry, the dark place at a temperature of no higher than 25 ° C

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