VENARUS PILLS 1G

Venotonic and venoprotective agent

ATH code: C05CA53

Pharmacological properties

Pharmacodynamics

Venarus® has an angioprotective and venotonic effect. It reduces the tensile properties of the veins, increases their tone and reduces venous stasis; reduces permeability, capillary fragility and increases their resistance; improves microcirculation and lymphatic drainage. With the systematic use reduces the severity of clinical manifestations of chronic venous insufficiency of the lower extremities of organic and functional nature. The optimal dose-effect ratio is observed when taking 1000 mg per day.

Pharmacokinetics

The main excretion of the drug occurs through the intestines. Through the kidneys, on average, about 14% of the accepted amount of the drug is excreted.

The half-life is 11 hours.

The drug Venarus® undergoes active metabolism, as evidenced by the presence of phenolic acids in the urine.

Indications

Venarus® is indicated for the treatment of symptoms of chronic venous disease (elimination and relief of symptoms).

Treatment of symptoms of venous lymphatic insufficiency:

- convulsions of the lower extremities;

- a feeling of heaviness and fullness in the legs;

- pain;

- "tired" legs.

Therapy of manifestations venous lymphatic insufficiency:

- swelling of the lower extremities;

- trophic changes in the skin and subcutaneous tissue;

- venous trophic ulcers.

Symptomatic therapy of acute and chronic hemorrhoids.

Contraindications

Hypersensitivity to the active ingredients or excipients that make up the drug. The drug is not recommended for women during breastfeeding.

Pregnancy and Breastfeeding

Pregnancy

Animal experiments revealed no teratogenic effects. To date, there have been no reports of any side effects when using the drug in pregnant women.

Breastfeeding period

Due to the lack of data on the elimination of the drug in breast milk, it is not recommended for women to take the drug during breastfeeding.

Reproductive Impact

Reproductive toxicity studies showed no effect on reproductive function in rats of both sexes.

Special notes

Before you start taking the drug Venarus®, it is recommended to consult with your doctor. In case of exacerbation of hemorrhoids, the prescription of the drug Venarus® does not replace the specific treatment of other anal disorders. The duration of treatment should not exceed the time specified in the section "Dosage and Administration". In the event that the symptoms do not disappear after the recommended course of therapy, a proctologist should be examined, who will select further therapy.

In the presence of disorders of the venous circulation, the maximum effect of treatment is provided by a combination of therapy with healthy(balanced) way of life: it is desirable to avoid a long stay in the sun, a long stay on your feet, and also the reduction of overweight is recommended. Walking and, in some cases, wearing special stockings, helps to improve blood circulation.

Seek medical attention immediately if your condition worsens during the treatment process or if there is no improvement.

Influence on ability to drive vehicles and mechanisms

Does not affect.

1 pill contains:

active ingredients:

hesperidin (in terms of 100% substance) 100 mg, diosmin (in terms of 100% substance) 900 mg;

excipients: microcrystalline cellulose 124 mg, sodium carboxymethyl starch (sodium starch glycolate) 54 mg, gelatin 62 mg, talc 12 mg, Magnesium stearate 8 mg;

excipients for the shell: hypromellose (hydroxypropyl methylcellulose 41.4 mg, macrogol 6000 (polyethylene glycol 6000) 6.76 mg, sodium lauryl sulfate 0.2 mg, magnesium stearate 2.48 mg, titanium dioxide 7.88 mg, iron red oxide 0, 6 mg, iron oxide yellow 0.68 mg.

Inside

The recommended dose for venous lymphatic insufficiency is 1 pill per day, preferably in the morning, during the meal. The risk on the pill is intended solely for dividing in order to facilitate swallowing.

The duration of the course of treatment can be several months (up to 12 months). In the case of recurrence of symptoms, according to the recommendation of the doctor, the treatment can be repeated.

The recommended dose for acute hemorrhoids is 3 pills per day (1 pill in the morning, afternoon and evening) for 4 days, then 2 pills per day (1 pill in the morning and evening) for the next 3 days.

The recommended dose for chronic hemorrhoids is 1 pill per day.

Adverse reactions

The incidence of adverse reactions is as follows: very often (≥1 / 10 cases), often (≥1 / 100 and <1/10 cases), infrequently (≥1 / 1000 and <1/100 cases), rarely (≥1 / 10,000 and <1/1000 cases) and very rarely (<1/10000 cases). Undesirable reactions, the frequency of development of which is not possible to estimate on the basis of available data, are designated as “frequency unknown”.

From the side of the central nervous system: rarely - dizziness, headache, general malaise.

On the part of the gastrointestinal tract: often - diarrhea, dyspepsia, nausea, vomiting; infrequently - colitis; frequency unknown - abdominal pain.

For the skin: rarely - rash, itching, urticaria; frequency is unknown - isolated swelling of the face, lips, eyelids, in exceptional cases, angioedema.

If any of the adverse reactions indicated in the instructions become worse, or you notice other adverse reactions not indicated in the instructions, inform your doctor.

Drug Interactions

Not noted.