PYRANTEL PILLS 250MG

Packaging

In the package 3 tablets.

Mechanism of action

Pyrantel is an anthelmintic agent acting on nematodes.

It causes neuromuscular blockade in worms that are sensitive to it, which facilitates their elimination from the digestive tract even without the additional use of laxatives.

The drug acts on parasites in the early phase of development and on their mature forms, does not affect the larvae during their migration in the tissues.

Pyrantel acts on the following nematodes:

- Enterobius vermicularis.
- Ascaris lumbricoides.
- Ancylostoma doudenale.
- Necator americanus.
- Trichostrongylus orientalis.
- Trichostrongylus colubriformis.

Indications and usage

- Ascariasis.
- Enterobiasis.
- Hookworm disease.

Contraindications

- Hypersensitivity to the drug.
- Myasthenia (treatment period).

With caution:

- Pregnancy.
- Lactation period.
- Liver failure.
- Children's age (up to 6 months).

Pregnancy and Breastfeeding

Pyrantel is contraindicated for use in pregnancy.

If necessary, use during lactation should decide on the termination of breastfeeding.

Dosage and administration

The drug is applied orally during or after a meal, carefully chewing the tablet, with 1 glass of water.

Depending on the age and weight of the patient, the following dosages are recommended:

In the case when infection with only the human nematode is noted, the pyrantel can be used in the lowest dose at one time 5 mg of active ingredient per 1 kg of body weight.

In case of ascariasis and enterobiasis, as well as mixed invasions by these parasites: The dose intended for the entire course (10 mg / kg body weight) is applied once.

In case of hookworm. The daily dose (10 mg / kg body weight) is used for 3 days.

For massive invasions of Necator americanus, a dose of 20 mg / kg of body weight is recommended for 2 days.

Note:
- When treating enterobiasis, the whole family should be treated at the same time.
- Careful hygiene is necessary.
- 14 days after treatment with Pirantel, control parasitological studies should be conducted.

Adverse reactions

Side effects are rare, they are short-lived and disappear after cessation of treatment.

On the part of the digestive tract: Nausea, vomiting, lack of appetite, diarrhea, pain and stomach cramps.

On the part of the central nervous system: Headache, dizziness, drowsiness, insomnia, weakness, rash, fever.

From the laboratory indicators: In rare cases, there is a transient increase in the concentration of AST in blood serum.

On the part of the senses: In isolated cases, hearing impairment, hallucinations with confusion and paresthesia were observed (the connection of these symptoms with the use of the drug has not been proven).

Pyrantel should not be used with piperazine. These agents act antagonistically.

Pyrantel increases plasma concentration of theophylline.

Overdosage

Cases of overdose are not described.

In case of overdose, symptomatic treatment should be undertaken.

The drug should be stored in a dry, dark place at temperatures below 25 ° C.

5 years.

Pyrantel