FUNGERBIN SPRAY 1% 30ML
FUNGERBIN SPRAY 1% 30ML
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Active ingredient and dosage form
1 pill contains Terbinafine 250 mg
Excipients: microcrystalline cellulose, kollidon CL-M, kollidon 30, aerosil, benzoic acid, Magnesium stearic acid.
10 or 14 pills per pack.
cream white or white with a yellowish tinge, with a slight specific smell.
1 g of cream contains 0.01 g of terbinafine hydrochloride.
Excipients: microcrystalline cellulose, kollidon CL-M, kollidon 30, aerosil, benzoic acid, magnesium stearic acid.
15 g in a tube.
- the active substance Fungosterina, is an allylamine and has a broad spectrum of antifungal action. Active against dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, Microsporum canis, Epidermophyton floccosum. In low concentrations, it has a fungicidal effect on dermatophytes, mold fungi (Aspergillus, Cladosporium, Scopulariopsis brevicaulis) and some dimorphic fungi. The activity against yeast fungi of the genus Candida and their mycelial forms, depending on the species, can be fungicidal or fungistatic.
Funterbinis also active in relation to Pityrosporum orbiculare (also called Malassezia furfur) is the causative agent of varicolor (pityriasis).
Funterbin disrupts the ergosterol synthesis in fungi by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus. This leads to a deficiency of ergosterol and to the intracellular accumulation of squalene, which causes the death of the fungal cell.
Terbinafine does not affect the synthesis of hormones and other drugs.
Indications and usage
- mycoses of the scalp (trichophytia, microsporia);
- treatment of widespread dermatomycosis of the trunk and extremities;
- candidiasis of the skin and mucous membranes caused by Candida fungi (in cases where the localization or prevalence of the process determines the appropriateness of oral therapy).
Dosage and administration
The duration of the course of treatment and the dosage regimen is set individually and depends on the localization process and the severity of the disease.
For adultsusually administered orally after a meal on a table. (250 mg) once a day.
Patients with hepatic and renal insufficiency - 1/2 pill (125 mg) 1 time per day.
Mycoses of the skin:recommended treatment duration: 2-6 weeks. The complete disappearance of the clinical manifestations of the disease is usually observed several weeks after mycological cure.
Mycoses of the scalp (observed mainly in children). The course of treatment is about 4 weeks.
The duration of the course of drug treatment in most patients is b - 12 weeks.The optimal clinical effect is observed several months after mycological cure and cessation of therapy. This is determined by the period of time that is necessary for the growth of a healthy nail.
Fungerbin cream is applied to the skin once or twice a day. Before applying the cream it is necessary to clean and dry the affected areas. The cream is applied in a thin layer on the affected skin and surrounding areas and lightly rubbed.
The average duration of treatment:Ringworm of trunk, legs: 1 week 1 time per day;Ringworm: 1 week 1 time per day Skin candidiasis: 1 - 2 weeks 1 or 2 times a day;Tonsolithus: 2 weeks 1 or 2 times a day.
For children, the drug is prescribed from the age of two.For children weighing up to 20 kg - 62.5 mg / day (1/4 tablet);from 20 kg to 40 kg- 125 mg / day (1/2 tablet);more than 40 kg - 250 mg / day (1 tablet).
Data on the use of the drug in children under two years of age (with a body weight less than 12 kg) is not available.
Hypersensitivity to terbinafine or any other component that is part of the drug.
Carefully - alcoholism, blood diseases, tumors, metabolic diseases, vascular pathology of the limbs. Children age - up to 2 years.
Irregular use or early termination of treatment increases the risk of recurrence.
If after 2 weeks of treatment there is no improvement in the condition, it is necessary to re-determine the causative agent and its sensitivity to the drug.Caution should be exercised in the appointment of Fungerbin inside the patient with impaired liver function and (or) kidney.
Funterbin pills are not effective in lichen colored.
In the process and at the end of treatment, it is necessary to produce antifungal treatment of shoes, socks and stockings.
Pregnancy and breastfeeding
Experience with the use of the drug during pregnancy is limited, so you should not use Fungerbin during pregnancy. Terbinafine is excreted in breast milk, so if necessary, the appointment of the drug is necessary to solve the issue of stopping breastfeeding.
Funterbin generally well tolerated. Side effects are usually mild or moderate and are transient. When ingestion can be observed:
From the gastrointestinal tract: dyspepsia, abdominal pain, feeling of fullness in the stomach, nausea, loss of appetite, diarrhea; sometimes a violation of taste, including their loss (restored after a few weeks after stopping treatment);
Musculoskeletal system: muscle pain, joint pain
Hemic and lymphatic:neutropenia, agranulocytosis, thrombocytopenia, rarely - lymphopenia.
Allergic reactions:skin rash in the form of spots, wheals, rarely toxic epidermal necrolysis, Stevens-Johnson syndrome, anaphylactoid reactions
List B. Store in a dry, dark, out of the reach of children.
Shelf life - 2 years.