CANDID B CREAM 1% 15G

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CANDID B CREAM 1% 15G

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Cream 1%: 1 g of cream contains Clotrimazole 10 mg;
Excipients: propylene glycol; liquid paraffin; cetomacrogol emulsion wax; white petrolatum; benzyl alcohol; methyl paraben; propyl paraben; anhydrous sodium phosphate; sodium phosphate monosubstituted; butylhydroxytoluene; purified water;
in aluminum tubes of 20 g; in a pack of cardboard 1 tube.

Solution for external use 1%:
1 ml of solution contains clotrimazole 10 mg;
in plastic bottles of 20 ml, in a cardboard box 1 bottle.

Powder for external use 1% white with a characteristic odor.
1 g of powder contains clotrimazole 10 mg;
in plastic bottles of 30 g, in a cardboard box 1 bottle.

Solution for topical use 1% colorless, transparent, viscous.
1 ml of solution contains clotrimazole 10 mg;
Excipients: propylene glycol - 495 mg; glycerin - 495 mg;
in dropper bottles of 15 ml, in a cardboard box 1 bottle

Cream white, uniform, semi-solid.
1 g of cream contains clotrimazole 10 mg, beclomethasone 250 mcg;
Excipients: white petrolatum jelly, liquid paraffin, tsetomakogol wax, benzyl alcohol, methylparaben, propylparaben, bottled hydroxytoluene, propylene glycol, monosodium phosphate, anhydrous sodium phosphate, purified water;
in aluminum tubes of 15 g, in a carton pack of 1 tube.

Vaginal tablets white, oval, biconvex, uncoated, with a monogram on one side and a "V6" sign on the other side.
1 pill contains clotrimazole 100 mg;
Excipients: lactose, dried corn starch, sodium starch glycolate, purified talc, Magnesium stearate, colloidal silicon dioxide, methyl hydroxybenzoate, propyl hydroxybenzoate, tartaric acid, sodium bicarbonate, povidone;
in a contourless package of 6 pcs., complete with an applicator; in the box 1 set.

cream - №008874 03/17/05
powder d / out. approx. - P No. 014637 / 01-2002 19.12.02
rr d / local applications - П №014637 / 02-2003 23.05.03
CANDID-Bcream - П №013699 / 01-2002 07.02.02
CANDID-B6 tab. vagin - P No. 012759/01-2001 11.03.01

Mechanism of action

Clotrimazole is an imidazole derivative, a broad-spectrum antifungal agent. Violates the synthesis of ergosterol, which is part of the cell membrane of fungi, which causes a change in its structure and properties and leads to cell lysis.
It also has antibacterial and antiprotozoal (trichomonacid) effects.
Dermatophytes, yeast fungi (genus Candida, Torulopsis glabrata, kind of Rhodotorula), mold fungi, as well as pathogen Pityriasis versicolor (lichen colored) and the causative agent of erythrasma.
In addition, it has an antimicrobial effect against gram-positive (staphylococci and streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis)as well as in relation to Trichomonas vaginalis, Malassezia furfur, Corynebacterium minutissimum.
Clotrimazole is characterized by a broad spectrum of fungicidal action, is active against dermatophytes (Trichophyton spp., Epidermophyton spp. and etc.), Candida spp., Aspergillus spp., Malassezia furfur and others, some strains of gram-positive and gram-negative bacteria.
CANDID-B
Combined preparation for external use.
Pharmachologic effect: local antifungal, local anti-inflammatory, antipruritic, anti-allergic, anti-exudative.
Clotrimazole is a broad-spectrum antifungal agent.
Beclomethasone - glucocorticoid, has anti-inflammatory, anti-allergic, anti-edema, anti-asthma effect.

When applied topically, clotrimazole penetrates well into various layers of the skin, reaching therapeutic concentrations.
When applied topically, a small amount of clotrimazole is absorbed into the blood.

Indications and usage

CANDID
- dermatophytosis of the head (including the face), body, legs;
- nail mycosis;
- lichen multi-colored;
- skin candidiasis;
- Candida paronychia;
- Candida vulvitis;
- Candida balanitis;
- candidiasis of the external genital organs and the anus;
- fungal diaper dermatitis;
- Erythrasma.

Fungal infections of the skin (including those complicated by acute eczematous symptoms):
- ringworm of various parts of the body;
- athlete's foot;
- dermatosis, complicated by secondary infection.

- Candida vulvovaginitis;
- trichomoniasis;
- genital superinfection caused by bacteria sensitive to clotrimazole (mixed infections of the vagina, bacterial vaginitis).

Contraindications

 
- specific skin lesions (including tuberculosis, chicken pox, herpes simplex, measles, syphilis);
- skin reactions at the vaccination site;
- hypersensitivity to the drug.

Dosage and administration

CANDID
The required amount of cream or lotion is rubbed onto the previously washed and dry affected skin area 2-3 times / day.
Treatment should be continued for 2-4 weeks after the disappearance of clinical symptoms in order to ensure mycological cure and prevent recurrence.
The drug in the form of a lotion is used for large lesions and hairy areas of the skin.
CANDID-B
Before applying the cream should be washed and dried the affected area. The cream should be applied directly to the affected areas, ensuring direct contact of the drug with the skin, incl. on hairy areas of the body. The drug is used 2-3 times / day.
After the disappearance of eczematous symptoms, it is recommended to switch to Candida treatment by the complete disappearance of the primary fungal infection.
CANDID-B6
Assign intravaginally 100 mg (1 tab.) 1 time / day (evening) for 6 days.
Vaginal pills should be inserted as deep as possible into the vagina. If necessary, the treatment can be repeated.

Adverse reactions

Local reactions: redness of the skin, burning sensation and tingling at the site of application of the drug (with the development of irritation, the drug must be canceled).
Maybe: allergic reactions.

Contraindications

 
- specific skin lesions (including tuberculosis, chicken pox, herpes simplex, measles, syphilis);
- skin reactions at the vaccination site;
- hypersensitivity to the drug.

Pregnancy and breastfeeding

The safety of the drug Candid during pregnancy and lactation has not been established. Therefore, you should avoid the appointment of the drug in large quantities or for a long time in these periods.

Special notes

The drug is intended for use only in dermatological practice.
It is necessary to avoid the use of the drug on the skin with a violation of the integrity of the skin.
It should be borne in mind that when external use of glucocorticoids on large areas of the skin or with occlusive dressings, their systemic absorption is possible.
With the use of occlusive dressings may develop rash, folliculitis, pyoderma.

To prevent urogenital reinfection it is necessary to simultaneously treat both sexual partners.
For trichomoniasis, it is recommended to combine local treatment with Candida B6 with systemic drugs (for example, metronidazole).
Vaginal pills are not recommended during menstruation.

Drug Interactions

With vaginal administration, Candid B6 reduces the activity of amphotericin B and other polyene antibiotics.
With simultaneous use with Nystatin, Candida B6 activity may decrease.

Storage conditions

The drug should be stored in a dry, dark place at a temperature not higher than 25 ° C.

Candid b

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