ACYCLOVIR OINTMENT 5% 5G

Composition

1 g ointment contains acyclovir 5 mg

Packaging

Tuba 5

Mechanism of action

Acyclovir is an antiviral drug, a synthetic analogue of the acyclic purine nucleoside, which has a highly selective effect on herpes viruses. Inside viral infected cells, viral thymidine kinase undergoes a series of consecutive transformations of acyclovir into mono-, di-, and acyclovir triphosphate. Acyclovir triphosphate is inserted into the viral DNA chain and blocks its synthesis through competitive inhibition of viral DNA polymerase. In vitro acycloviractive against Herpes simplex type 1 and 2, Varicella zoster; higher concentrations are required to inhibit Epstein-Barr virus. In vivo acyclovir is therapeutically and prophylactically effective primarily in viral infections caused by Herpes simplex.

Indications and usage

Herpes simplex skin; prevention of infections caused by the herpes simplex virus in patients with impaired immune systems; genital herpes (primary and recurrent); shingles; chickenpox.

Contraindications

Hypersensitivity to the drug.

Dosage and administration

Ointment Acyclovir is applied to the affected surface 5 times / day (after 4 hours). The duration of treatment is 5-10 days.

Adverse reactions

Allergic reactions: allergic dermatitis
Local reactions: When applying the ointment, it is possible - redness, itching, peeling, burning or stinging.

The ointment is not recommended to be applied to the mucous membranes of the mouth, eyes, genitals, because possible development of pronounced local inflammation.
The effectiveness of treatment when applying the ointment will be the higher, the earlier it is started.
In patients with immunodeficiency with repeated repeated courses of treatment, viruses are sometimes resistant to acyclovir.

Storage conditions

Store in a dry, dark place at a temperature of 8 ° to 15 ° C.