KAMIREN PILLS 2MG

Active ingredient and dosage form

Kamiren - tablets: 1 pill contains Doxazosin 1, 2, or 4 mg; in a blister strip packaging 10 pcs., in a cardboard bundle 2 or 3 packs.

Mechanism of action

Kamiren has a hypotensive, vasodilator, lipid-lowering, antispasmodic action. Selectively blocks postsynaptic alpha1-adrenoreceptors. It lowers the OPSS, the level of total cholesterol, LDL and triglycerides and increases the content of HDL in the serum. It prevents the development of atherosclerosis and IHD, inhibits platelet aggregation. Kamiren reduces the mass of the left ventricle (with long-term treatment). It prevents the contraction of the smooth muscles of the upper part of the urethra and the muscles of the prostate gland, facilitates urination and eliminates the dysuric symptoms accompanying benign prostatic hyperplasia.

Indications and usage

Arterial hypertension of mild or moderate severity (monotherapy or in combination with other antihypertensive drugs), benign prostatic hyperplasia (symptomatic treatment).

Contraindications

Hypersensitivity, incl. to other derivatives of quinazoline (prazosin, terazosin) or to other components of Kamiren, obstruction of the gastrointestinal tract or esophagus, narrowing of the gastrointestinal tract of any degree, children's age.

Pregnancy and Breastfeeding

Perhaps if the expected effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Adverse reactions

Since the cardiovascular system and blood (hematopoiesis, hemostasis): arterial hypotension (especially at the beginning of treatment and increasing the dose of Kamiren when moving from a prone position or sitting to a standing position), very rarely - exacerbation of angina, myocardial infarction, cerebrovascular stroke, heart rhythm disturbance (however, it was not established that doxazosin was the cause); thrombocytopenia.

On the part of the respiratory system: nasal congestion or nasal discharge, flu-like symptoms, bronchitis, shortness of breath.

On the part of the gastrointestinal tract: very rarely - nausea, cholestasis, hepatitis, impaired liver function indicators.

On the part of the musculoskeletal system: muscle weakness.

From the nervous system and sensory organs: dizziness, headache, fatigue, drowsiness.

For the skin: very rarely - skin rash, purpura.

Other: hematuria, nasal bleeding, swelling of the ankles and legs.

Dosage and administration

Kamiren take orally, regardless of the meal.

Arterial hypertension and benign prostatic hyperplasia in patients with arterial hypertension: the initial dose (in the evening before bedtime) is 1 mg per day with a gradual increase to 2, 4 and 8 mg once a day with an interval of 1-2 weeks.The usual daily dose of Kamiren is 2-8 mg, the maximum is 16 mg. Benign prostatic hyperplasia in patients with normal blood pressure: initial dose (in the evening before bedtime)

1 mg / day with a gradual increase to 2, 4 and 8 mg 1 time per day (interval - 1-2 weeks). The average daily dose - 2-4 mg, maximum - 8 mg.

Storage conditions

In the dark place at a temperature of no higher than 25 ° C. Shelf life - 5 years.