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- prevention and long-term treatment of angina III-IV functional classes;

- rehabilitation treatment after myocardial infarction;

- treatment of chronic heart failure (as part of combination therapy).

Dosage and administration

Monochinkve® retard appoint 50 mg (1 capsule.) 1 time / day in the morning after eating, without chewing and washing down with a small amount of liquid.

The dose should be adjusted depending on the condition of the patient.

Adverse effects

When taking Monocinque ® retard in the recommended dose side effects are not described.

However, as with the use of other nitrates, it is possible:

Cardiovascular: at the beginning of treatment - a "nitrate" headache, which usually decreases after a few days with continued therapy; after the first dose or after increasing the dose - arterial (including orthostatic) hypotension, accompanied by tachycardia, dizziness, weakness.

Gastrointestinal: very rarely - nausea, vomiting.

Dermatologic: very rarely - facial flushing and skin allergic reactions.


- acute circulatory disorders (shock, vascular collapse);

- hemorrhagic stroke;

- acute stage of myocardial infarction;

- simultaneous administration of phosphodiesterase inhibitors (sildenafil);

- severe arterial hypotension (systolic blood pressure <90 mm Hg, diastolic blood pressure <60 mm Hg);

- states after traumatic brain injury;

- angle-closure glaucoma;

- deficiency of glucose-6-phosphate dehydrogenase;

- age up to 18 years;

- hypersensitivity to organic nitrates.

Use during pregnancy and lactation

In pregnancy, the drug can be prescribed only under strict indications, when the expected therapeutic effect for the mother outweighs the potential risk to the fetus.

If there is a need for the drug during lactation, then breastfeeding should be stopped.

Use in children

Contraindicated in children and adolescents under 18 years of age.

Special notes

The drug is not used for the relief of strokes.

For hypertension, the drug is used only under the supervision of a physician.

The drug is prescribed both as monotherapy and in combination with beta-blockers, Calcium channel blockers, ACE inhibitors, cardiac glycosides or diuretics.

Influence on ability to drive motor transport and control mechanisms

When taking the drug may reduce the ability to concentrate and the speed of psychomotor reactions, and therefore it is not recommended to drive vehicles and engage in other potentially dangerous activities.


No cases of overdose have been reported.However, when symptoms of overdose occur, generally accepted measures are recommended: induce vomiting, flush the stomach. It is necessary to control whether the patient has taken any other medicines at the same time, to monitor the hemodynamic parameters.

Drug interaction

With simultaneous reception Monocinque® retard with other vasodilators, antihypertensive drugs, beta-blockers, calcium channel blockers, antipsychotics, tricyclic antidepressants, Sildenafil, ethanol, potentiation of the monocinkve hypotensive effect is possible® retard.

Terms and conditions of storage

The drug should be stored in a dark, out of reach of children at a temperature not higher than 25 ° C.

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