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Active ingredient and dosage form

Presartan - tablets, film-coated pink, round, biconvex, with dividing risks on one side:

1 tab. contains Losartan potassium 25 and 50 mg; 10, 14, 20, 28, 30 or 42 pieces per pack.

Mechanism of action

Antihypertensive drug, a specific angiotensin type II receptor antagonist (AT2). Presartan does not inhibit kinase II, an enzyme that destroys bradykinin. Decreases round fist, reduces afterload, reduces systemic blood pressure and pressure in the pulmonary circulation.

Indications and usage

- arterial hypertension;

- Ischemic heart disease, accompanied by symptoms of heart failure (in combination therapy with diuretics and cardiac glycosides).

Dosage and administration

The initial daily dose of Presartan is 25 mg, the average daily dose is 50 mg, the frequency of administration is 1 time / day.

Adverse reactions

On the part of the digestive system: diarrhea, dyspepsia; rarely, an increase in liver transaminase activity and blood bilirubin levels.

From the side of the central nervous system: dizziness, sleep disturbance, headache.

On the part of the respiratory system: rarely - breathing problems, cough.

Allergic reactions: rarely - angioedema (including swelling of the face, lips, pharynx and / or tongue), urticaria.

Other: myalgia, edema, hyperkalemia (potassium in the blood of more than 5.5 mEq / l); rarely - tachycardia.

Susartan is usually well tolerated.


- children's and teenage age up to 18 years;

- pregnancy;

- hypersensitivity to the components of Desartan.

Special notes

In patients with dehydration (for example, with high-dose diuretic therapy), symptomatic arterial hypotension may occur at the beginning of treatment with Presartan. It is necessary to carry out the correction of water and electrolyte balance before the appointment of Presartan or to begin treatment with a low dose.

Storage conditions

At temperatures not above 25 ° C. Shelf life - 3 years.

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