DALNEVA PILLS 10MG + 4MG

$36.10
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DALNEVA PILLS 10MG + 4MG - 30 tabs

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Indications and usage

Arterial hypertension and / or coronary artery disease: stable exertional angina (in patients who require Perindopril and amlodipine).

Contraindications
Amlodipine
Severe arterial hypotension: systolic blood pressure less than 90 mm Hg.
Shock:
Including cardiogenic shock.
Obstruction of the output tract of the left ventricle:
For example, severe aortic stenosis.
Unstable angina, with the exception of Prinzmetal angina.
Age up to 18 years: efficiency and safety have not been established.
Hemodynamically unstable heart failure after acute myocardial infarction.
Hypersensitivity to amlodipine or other dihydropyridine derivatives.
Perindopril
Angioedema (angioedema) in history, including while taking other ACE inhibitors.
Hereditary / idiopathic angioedema.
Age up to 18 years: efficiency and safety have not been established.
Hypersensitivity to perindopril or other ACE inhibitors.
Dal'neva
Renal failure (CC less than 60 ml / min).
Age up to 18 years: efficiency and safety have not been established.
Hypersensitivity to the drug.

 

Mode of application

Inside, 1 pill 1 time per day, preferably in the morning before a meal. The dose of the Dal'nev drug is selected after a previous titration of the doses of the individual components of the drug: perindopril and amlodipine in patients with arterial hypertension and stable angina. If necessary, the dose of the drug Dalnev can be changed, based on individual selection of doses of individual components: (amlodipine 5 mg + perindopril 4 mg) or (amlodipine 10 mg + perindopril 4 mg) or (amlodipine 5 mg + perindopril 8 mg) or (amlodipine 10 mg + perindopril 8 mg).

Maximum Daily Dose

Amlodipine 10 mg + perindopril 8 mg.

Use in special clinical situations
The drug Dalnev can be prescribed to patients with CC more than 60 ml / min. The drug Far is contraindicated for use in patients with QA less than 60 ml / min. Such patients are recommended individual selection of doses of perindopril and amlodipine. Changes in the concentration of amlodipine in the blood plasma do not correlate with the severity of renal failure.

Care must be taken 

When using the drug Dalnev in patients with liver failure, because there are no recommendations for the doses of the drug in these patients.

When using the drug Dalnev in elderly patients, dose adjustment is not required.

Dalnev's drug should not be prescribed to children and adolescents under 18 years, because there are no data on the efficacy and safety of perindopril and amlodipine in these groups of patients both in monotherapy and as part of combination therapy.

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