URDOX CAPSULES 250MG

$41.50
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URDOX CAPSULES 250MG - 50 pcs

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Composition and release form

Capsules:
1 capsule contains 250 mg ursodeoxycholic acid;
excipients: corn starch, anhydrous colloidal silicon dioxide, Magnesium stearate;
capsule composition: gelatin, methylhydroxybenzoate, propylhydroxybenzoate, titanium dioxide.;
in the package 50 or 100 pcs.

pharmachologic effect

Urdoksa - hepatoprotective drug. It also has choleretic, cholelitholytic, hypocholesterolemic, immunomodulatory effects.

It is embedded in the hepatocyte membrane, stabilizes its structure and protects the hepatocyte from the damaging effects of bile salts, thus reducing their cytotoxic effect. Contributes to the partial or complete dissolution of cholesterol gallstones by oral administration

Indications

Cholesterol gallstones,
hepatitis (chronic, including atypical forms of chronic autoimmune, acute viral),
nonalcoholic steatohepatitis, toxic (including alcoholic, medicinal) liver damage,
primary biliary cirrhosis and liver cystic fibrosis,
primary sclerosing cholangitis,
atresia of the intrahepatic biliary tract,
cholestasis with parenteral nutrition,
biliary dyskinesia,
biliary reflux gastritis and reflux esophagitis;
chronic opisthorchiasis;
prevention of liver damage when using hormonal contraceptives and cytostatics.

Contraindications

Hypersensitivity, acute inflammatory diseases of the gallbladder, bile ducts and intestines, complete obstruction of the biliary tract, calcified gallstones, cirrhosis of the liver in the stage of decompensation, marked impairment of renal function, pancreas, pregnancy and lactation; childhood.

Dosage and administration

The dosage regimen and the duration of treatment are set individually. The average dose of 8-10 mg / kg / day. The daily dose is taken orally once in the evening (without chewing and washing down with a sufficient amount of liquid).

Side effects

Back pain, abdominal pain, diarrhea (can be dose-dependent).

Rarely - calcification of gallstones, transient (transient) increase in the activity of hepatic transaminases, constipation, nausea, vomiting, alopecia, dizziness, exacerbation of previously existing psoriasis, allergic reactions, including hives.

special instructions

For successful litholysis with ursodeoxycholic acid, the following conditions must be met: the stones must be purely cholesterol, i.e. do not give a shadow on the radiograph; the size of the stones should not exceed 15-20 mm; the gallbladder must fully preserve its function; the gallbladder must be filled with no more than half of the stones; patency of the cystic duct should be maintained; the common bile duct should be free from stones.

When using ursodeoxycholic acid to dissolve gallstones in the first 3 months of treatment, it is necessary to determine the activity of liver transaminases every 4 weeks. In the future, these studies can be carried out with an interval of 3 months.
To control the effectiveness of the treatment, it is recommended that x-ray and ultrasound examination of the biliary tract be performed every 6 months.
To prevent the recurrence of cholelithiasis, treatment should continue for several months after the gallstones dissolve.

Storage conditions

In the dark place at a temperature of no higher than 25 ° C.

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