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Trade name: 

Tantum® Verde

International non-proprietary name:


Dosage Form: 



For one lozenge:

The active ingredient benzydamine hydrochloride - 3 mg

Auxiliary ingredients: isomaltose 3183 mg, racecentol 4 mg, aspartame 3.5 mg, citric acid, monohydrate 2 mg, mint flavor 5 mg, lemon flavor 1.5 mg, quinoline yellow dye (E104) 0.035 mg, indigo carmine dye (E132) 0.015 mg.


Pharmacotherapeutic group: nonsteroidal anti-inflammatory drug

Pharmacological properties


Benzydamine is a nonsteroidal anti-inflammatory drug that belongs to the group of indazoles. It has anti-inflammatory and local anesthetic effect, has an antiseptic effect against a wide range of microorganisms. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis.

Benzydamine has an antibacterial and specific antimicrobial effect due to the rapid penetration of microorganisms through the membranes with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes.

It has antifungal effects against Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, thus, prevents their reproduction, which was the basis for the use of benzydamine in inflammatory processes in the oral cavity, including infectious etiology.


When applied topically, the drug is well absorbed through the mucous membranes and penetrates into the inflamed tissue, is detected in the blood plasma in an amount insufficient to obtain systemic effects.

Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products.

Indications for use

Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies):

- gingivitis, glossitis, stomatitis (in including after radiation and chemotherapy);

- pharyngitis, laryngitis, tonsillitis;

- candidiasis oral mucosa (as part of combination therapy);

- calculous inflammation of the salivary glands;

- after surgery and injuries (tonsillectomy, fractures of the jaw)

- after treatment and removal of teeth;

- periodontal disease;

In infectious and inflammatory diseases that require systemic treatment, Tantum® Verde should be used as part of a combination therapy.


- Hypersensitivity to benzydamine or other components of the drug;

- fructose intolerance;

- children's age up to 6 years;

- phenylketonuria


Hypersensitivity to Acetylsalicylic acid or other nonsteroidal anti-inflammatory drugs, bronchial asthma (including a history of).

Pregnancy and breastfeeding

The drug Tantum® Verde should not be used during pregnancy and during breastfeeding.

Dosage and administration

Locally, after meals. Adults (including elderly patients) and children over 6 years old: 1 pill for sucking 3 times a day. pills hold in the mouth until dissolved. Do not swallow. Do not chew. Do not exceed the recommended dose. For children from 6 to 12 years old, the use of the drug is made under the supervision of an adult.

The duration of treatment should not exceed 7 days. If after treatment within 7 days of improvement does not occur or new symptoms appear, you should consult with your doctor.

Use the drug only according to the method of use and in those doses that are indicated in the instructions. If necessary, please consult a physician before using the drug.

Side effects:

Classification of the incidence of side effects of the World Health Organization (WHO):

very often - ≥1 / 10;

often from ≥ 1/100 to <1/10;

infrequently - from ≥1 / 1000 to <1/100;

rarely from ≥1 / 10000 to <1/1000;

very rarely - <1/10000;

frequency unknown - cannot be estimated based on available data.

In each group, undesirable effects are presented in order of decreasing severity.

Local reactions: rarely - dry mouth, burning in the mouth; frequency unknown — numbness in the mouth.

Allergic reactions: infrequently - photosensitivity; rarely, hypersensitivity reactions. skin rash, pruritus; very rarely - angioedema, laryngospasm; frequency unknown - anaphylactic reaction.

If any of the side effects indicated in the instructions are aggravated, or any other side effects that are not indicated in the instructions are noted, you should immediately inform your doctor.


Currently, no cases of overdose of Tantum® Verde have been reported.

Symptoms: when using the drug in accordance with the instructions for use of an overdose is unlikely. If the drug is swallowed accidentally, the following symptoms may occur: vomiting, abdominal cramps, anxiety, fear, hallucinations, convulsions, ataxia, fever, tachycardia, respiratory depression.

Treatment: symptomatic; empty the stomach, causing vomiting or flushing the stomach, using a stomach tube (under the supervision of a physician); provide medical observation, maintenance therapy and necessary hydration. Antidote not known.

Interaction with other drugs

Research interaction with other drugs was not conducted.

Special notes

At use of the drug Tantum® Verde development of reactions of hypersensitivity is possible.In this case, it is recommended to discontinue treatment and consult a physician for appropriate therapy.

In a limited number of patients, the presence of ulcers in the throat and oral cavity may indicate the presence of a more serious pathology. If symptoms persist for more than 3 days, you should consult with your doctor.

Use of the drug Tantum® Verde is not recommended in patients with hypersensitivity to acetylsalicylic acid or other nonsteroidal anti-inflammatory drugs.

Tantum® Verde should be used with caution in patients with a history of bronchial asthma because they may develop bronchospasm while taking the drug.

The drug contains isomaltose and, therefore, is not recommended in patients with hereditary fructose intolerance.

Use of the drug in children is possible only under the supervision of adults in order to avoid swallowing the pill.

Influence on ability to steer vehicles, mechanisms

Does not affect the ability to drive vehicles and work with mechanisms.

Shelf life

4 years

Do not use after expiration date.

Storage conditions

At a temperature not higher than 25 ° С, protected from light.

Keep out of the reach of children.

Vacation conditions


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