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COSMETIC BRANDS
URSOFALK SUSPENSION 250MG/5ML 250ML
URSOFALK SUSPENSION 250MG/5ML 250ML
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Dosage form
Oral suspension
Composition
Active substance: Ursodeoxycholic acid 250 mg.
Excipients: benzoic acid, Avicel RC 591, sodium chloride, sodium citrate, citric acid, glycerin, propylene glycol, xylitol, sodium cyclamate, lemon flavoring Givaudan 87017, purified water.
Packaging
250 ml
Mechanism of action
Ursofalk - hepatoprotector.
It has a choleretic effect. Reduces the synthesis of cholesterol in the liver, its absorption in the intestines and concentration in bile, increases the solubility of cholesterol in the biliary system, stimulates the formation and excretion of bile. Reduces the lithogenicity of bile, increases the content of bile acids. It causes increased gastric and pancreatic secretion, enhances the activity of lipase. It has a hypoglycemic effect.
It causes partial or complete dissolution of cholesterol stones when taken orally, reduces the saturation of bile with cholesterol, which helps mobilize cholesterol from their gallstones.
It has an immunomodulatory effect, affects immunological reactions in the liver: reduces the expression of certain antigens on the hepatocyte membrane, affects the number of T-lymphocytes, the formation of interleukin-2, reduces the number of eosinophils.
Indications and usage
Dissolving cholesterol gallstones.
Biliary reflux gastritis.
Primary biliary cirrhosis in the absence of signs of decompensation (symptomatic treatment).
Contraindications
X-positive (high calcium) gallstones.
Nonfunctioning gallbladder.
Acute inflammatory diseases of the gallbladder, bile ducts and intestines.
Liver cirrhosis in decompensation.
Severe renal dysfunction.
Severe abnormal liver function.
Pronounced dysfunction of the pancreas.
Pregnancy.
Lactation period (breastfeeding).
Hypersensitivity to the drug.
Dosage and administration
To dissolve cholesterol gallstones, 10 mg / kg of body weight 1 time / day is prescribed.
The duration of treatment is 6-12 months.
For the prevention of re-cholelithiasis, it is recommended to take the drug for several months after the stones dissolve.
For the treatment of biliary reflux gastritis, 1 scoop of Ursofalk is prescribed 1 time per day. The course of treatment - from 10-14 days to 6 months, if necessary - up to 2 years.
For symptomatic treatment of primary biliary cirrhosis, the daily dose depends on body weight and ranges from 2 to 6 scoops (approximately 10-15 mg / kg body weight).
Storage conditions
The drug is stored at a temperature of from 0 to 25 º C.
Ursofalk