GALAVIT PILLS 25MG

Immunomodulatory agent

Mechanism of action

The mechanism of action of Galavit is associated with the ability to affect the functional-metabolic activity of macrophages.

In inflammatory diseases, it reversibly (for 6-8 hours) inhibits the excessive synthesis of tumor necrosis factor, interleukin-1 and other pro-inflammatory cytokines, active oxygen species by hyperactive macrophages, which determine the degree of inflammatory reactions, their cyclicity, and the severity of intoxication. Normalization of the functional state of macrophages leads to the restoration of antigen-presenting and regulating function of macrophages, reducing the level of auto-aggression.

The drug stimulates the bactericidal activity of neutrophilic granulocytes, increasing phagocytosis and increasing the body’s non-specific resistance to infectious diseases.

Pharmacokinetics

Excreted mainly by the kidneys. With sublingual use T1/2 makes 30 min.

The main pharmacological effects are observed within 72 hours.

Indications

As an immunomodulator and anti-inflammatory agent in the complex therapy of immunodeficiency states in adults and adolescents over 12 years old:

- Infectious intestinal diseases accompanied by intoxication and / or diarrhea;

- gastric ulcer and duodenal ulcer;

- viral hepatitis;

- chronic recurrent diseases caused by the herpes virus;

- Diseases caused by human papillomavirus;

- infectious and inflammatory diseases of the urogenital tract (urethritis of chlamydial and trichomonas etiology, chlamydial prostatitis, acute and chronic salpingoophoritis, endometritis);

- purulent-inflammatory diseases of the pelvic organs;

- postoperative rehabilitation of patients with uterine myoma;

- Complications of the postoperative period in patients of reproductive age;

- purulent surgical diseases (burn lesions, chronic osteomyelitis, gangrenous appendicitis with omentitis, peritonitis, purulent pleurisy);

- postoperative purulent-septic complications and their prevention (including in cancer patients);

- Chronic recurrent furunculosis, erysipelas;

- asthenic conditions, neurotic and somatoform disorders, reduced physical performance (including athletes);

- Mental, behavioral and post-abstinence disorders in alcohol and drug addiction;

- inflammatory diseases of the mucous membranes of the mouth and throat, periodontal disease;

- frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (including frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis) and their prevention.

Dosage and administration

Sublingual on 1 tab. daily up to 4 times / day or 2 tab. daily up to 2 times / day, depending on the diagnosis and the severity of the disease.

At acute infectious intestinal diseases involving diarrhea syndrome, the initial dose is 2 tab. once, then - 1 tab. 3-4 times / day before relief of symptoms of intoxication within 3-5 days.

At gastric ulcer and duodenal ulcer in the acute period in the first 2 days you should take 1 tab. 4 times / day, then every 3 days, 1 tab. 4 times / day, course of 2-3 weeks. AT chronic period take within 5 days on 1 tab. 4 times / day, then every 3 days, 1 tab. 4 times / day course up to 3 weeks.

At viral hepatitis of various etiologies in the acute period of the disease, the initial dose is 2 tab. 2 times / day to relieve symptoms of intoxication and inflammation. Perhaps the subsequent continuation of the course on 1 tab. 4 times / day every 3 days with a course of up to 2-3 weeks.

At chronic recurrent diseases caused by the herpes virus - 1 tab. 4 times / day for 10 days. Then - 1 tab. 4 times / day every other day for 10 days.

At human papillomavirus diseases should take 5 days for 1 tab. 4 times / day, then - 1 tab. 4 times a day through the course of up to 2-3 weeks.

At urogenital diseases (urethritis of chlamydial and trichomonas etiology, chlamydial prostatitis) on the first day, 2 tab. 2 times / day, then - 1 tab. 4 times / day every other day with a course of up to 2 weeks (depending on the severity of the pathological process).

At salpingoophoritis, endometritis in the acute period - 2 tab. 2 times / day for 2 days, then - 1 tab. 4 times / day every 3 days for 3 weeks. AT chronic period - within 5 days on 1 tab. 4 times / day, then - 1 tab. 4 times / day every 3 days with a course of up to 2-3 weeks.

At acute and chronic purulent diseases of the pelvic organs in the acute period on the first day, 2 tab. 2 times / day, then - 3 days on 1 tab. 4 times / day, then - 1 tab. 4 times / day every other day for 10 days. AT chronic period - within 5 days on 1 tab. 4 times / day, then - 3-4 pills / day every 3 days with a course of up to 3 weeks.

For postoperative rehabilitation of patients with uterine myoma and with complications of the postoperative period in women of reproductive age the drug should be taken within 5 days on 1 tab. 4 times / day, then - 1 tab. 4 times a day every other day with a course of up to 2 weeks.

At purulent surgical diseases (burn lesions, chronic osteomyelitis, gangrenous appendicitis with omentitis, peritonitis, purulent pleurisy) apply 4 times / day for 1 tab. for 5 days, then - 1 tab. 4 times a day with a course of up to 15 days.

For prevention and treatment of surgical complications in the pre- and postoperative period (including in cancer patients) appoint 1 tab. 4 times / day for 5 days before surgery, within 10 days after surgery, 1 tab. 4 times a day and for 3 weeks 1 tab. 4 times in 3 days. In severe cases of the disease - on the first day, 2 tab. 2 times / day.

At chronic recurrent furunculosis, erysipelas - 5 days on 1 tab. 4 times / day, then - 1 tab. 4 times a day with a course of up to 3 weeks.

At asthenic conditions, neurotic and somatoform disorders, with mental, behavioral and post-abstinent disorders in patients with alcohol and drug addiction - 5 days on 1 tab. 4 times / day, then - 1 tab. 4 times every 3 days for 3 weeks.

For increase physical performance - 1 tab. 4 times a day for 10 days, then 1 tab. 4 times / day in 3 days with a course of up to 3 weeks.

At inflammatory diseases of the mucous membranes of the mouth and throat, periodontal diseases initial dose of 1 tab. 4 times / day for 5 days, then 1 tab. 4 times / day in 3 days with a course of up to 3 weeks.

At frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent SARS, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis) apply 4 times / day for 1 tab. for 5 days, then - 1 tab. 4 times a day with a course of up to 15 days.

For prevention of acute respiratory infections and flu - 1 tab. 2 times / day. The course is 5-10 days.

Side effect

Seldom: allergic reactions are possible.

Contraindications

- pregnancy;

- lactation period;

- individual intolerance.

Use during pregnancy and lactation

The use of the drug is contraindicated in pregnancy and lactation.

Use in children

The drug is intended for use in adults and adolescents over 12 years.

Special notes

With simultaneous use with the drug Galavit® possible reduction of course doses of antibiotics.

Overdosage

Data overdose available.

Drug interaction

Cases of incompatibility with other drugs are not marked.

Terms and conditions of storage

The drug should be stored out of the reach of children, protected from light at a temperature not higher than 25 ° C. Shelf life - 3 years.

Pharmacy sales terms

The drug is approved for use as a means of OTC.