GUTTASIL PILLS 7.5MG

Release form

Pills

Mechanism of action

Guttasil is a laxative.

Indications and usage

Constipation or cases requiring relief of bowel movements (hemorrhoids, proctitis, anal fissures, preparation for surgical interventions, instrumental and X-ray studies).

Contraindications

• hypersensitivity to sodium picosulfate and other components of the drug;
• intestinal obstruction;
• acute inflammatory bowel diseases and acute diseases of the abdominal organs (including acute appendicitis, ulcerative colitis, peritonitis);
• acute abdominal pain, accompanied by nausea and vomiting, which may indicate acute inflammatory diseases, severe dehydration;
• pregnancy (I term);
• lactation period.

Pregnancy and Breastfeeding

II-III trimesters of pregnancy.

Special notes

Like other laxatives, Guttasil should not be taken daily for a long time. If necessary, daily intake of laxatives should find out the cause of constipation. Prolonged use of laxatives can lead to electrolyte imbalance and hypokalemia, as well as cause addiction and constipation due to the effect of rebound.
Guttasil is effective in eliminating constipation in cancer patients receiving large doses of opioids.
The drug contains sorbitol, therefore it is not recommended to take it to patients with rare hereditary fructose intolerance.
Influence on ability to drive motor transport and work with mechanisms. In therapeutic doses, the drug does not affect the ability to drive vehicles and work with other mechanisms.

Composition

1 tab. sodium picosulfate 7.5 mg

Excipients: sorbitol 460 mg, sodium methyl paraoxybenzoate 2.0 mg, hydrochloric acid 1 M to pH 6.0-7.0, water d / and up to 1 ml.

Dosage and Administration

The drug should be taken orally, at night (so that the chair was the next morning).

Adverse reactions

Skin: skin rash, urticaria, itching.
From the side of water and electrolyte balance: loss of potassium, sodium and other electrolytes, the development of dehydration is possible.
On the part of the digestive system: dyspepsia, vomiting, nausea, cramps and abdominal pain, diarrhea, flatulence, pain in the stomach and anus, increased intestinal motility, which pass with a decrease in the dose of the drug.
On the part of the immune system: allergic reactions, angioedema.
From the side of the central nervous system: headache, fatigue, drowsiness, convulsions.

Drug Interactions

Electrolyte imbalance can lead to impaired tolerance to cardiac glycosides.Diuretics or corticosteroids can increase the severity of hypokalemia caused by the use of Guttasil in high doses. Simultaneous antibiotic treatment may reduce the laxative effect of the drug.

Overdosage

Symptoms: High doses of Guttasil can cause liquid bowel movements, abdominal cramps (colic) and clinically significant impairments of water and electrolyte balance (hypokalemia, loss of other electrolytes and fluids), ischemia of the mucous membrane of the large intestine. Prolonged overdose leads to the development of chronic diarrhea and abdominal pain, hypokalemia, secondary hyperaldosteronism, kidney damage and the development of nephrolithiasis, metabolic alkalosis, hypokalemia and muscle weakness as a result of hypokalemia.

gastric lavage, administration of enterosorbents (activated carbon), symptomatic treatment (correction of water and electrolyte balance, prescription of antispasmodics).

In the dark place at a temperature of 15-25 ° C.