CAFFEINE SODIUM BENZOATE AMPOULES 20% 1 ML

Active ingredient

1 pill contains caffeine (in the form of sodium benzoate) 0.1 or 0.2 g;
in a blister strip package 10 pcs.

1 ml contains caffeine (in the form of sodium benzoate) 0.1 or 0.2 g;
in 1 and 2 ml ampoules, in a package 10 pcs.

Mechanism of action

Analeptic, psychostimulant, cardiotonic. It has a stimulating effect on the central nervous system, increases the reflex excitability of the spinal cord, stimulates the respiratory and vasomotor centers, regulates and strengthens the processes of excitation in the cerebral cortex. Increases mental and physical performance, reduces fatigue and drowsiness. Increases strength and heart rate (especially in large doses), increases blood pressure during hypotension (does not change normal). Expands blood vessels of skeletal muscles, heart, kidneys, bronchi, narrows - the abdominal organs. Increases the secretory activity of the stomach. Lowers platelet aggregation. It has a moderate diuretic effect. Blocks central and peripheral adenosine receptors. Stabilizes transmission at dopaminergic synapses, beta-adrenergic synapses of the hypothalamus and medulla oblongata, cholinergic synapses of the cortex and medulla oblongata, noradrenergic synapses.The action of the drug largely depends on the type of nervous system in the patient, therefore, the dosing of caffeine must take into account the individual characteristics of the nervous activity.

Indications and usage

Diseases accompanied by inhibition of the functions of the central nervous system, cardiovascular system, respiratory system (drug poisoning, infectious diseases, etc.). When spasms of cerebral vessels, to increase mental and physical performance, to eliminate drowsiness, respiratory disorders, enuresis in children.

Contraindications

Severe arterial hypertension, organic diseases of the cardiovascular system (including atherosclerosis), irritability, glaucoma, sleep disorders, old age. Side effects
Anxiety, agitation, insomnia, tachycardia, arrhythmias, high blood pressure, nausea, vomiting. With prolonged use may be slightly addictive (a decrease in the action of caffeine is associated with the formation of new adenosine receptors in brain cells). A sudden cessation of caffeine can lead to increased inhibition of the central nervous system with symptoms of fatigue, drowsiness and depression.

Dosage and administration

Inside - on 0,025-0,1 g 2-3 times a day.
For adults subcutaneously - 1 ml of 10 or 20% solution 2-3 times a day;
for children (depending on age) - 0.25-1 ml of 10% solution 2-3 times a day.
The highest single dose for adults - 0.4 g, daily - 1 g.

Drug interactions

Reduces the effect of hypnotics and drugs, increases (improving bioavailability) - Acetylsalicylic acid, Paracetamol and other non-narcotic analgesics. Improves absorption of ergotamine in the digestive tract.

Overdosage

If caffeine is abused (more than 300 mg per day, that is, four cups of natural coffee, 150 ml each), it can cause anxiety, anxiety, tremor, headache, confusion, and cardiac extrasystoles. In newborns (including premature infants), at a plasma concentration of 50 mg / ml, toxic effects are possible: anxiety, tachypnea, tachycardia, tremor, increased Moro reflex, with higher concentrations - convulsions.

Storage conditions

: List B. In the dark spot

Caffeine sodium benzoate