BARALGIN M PILLS
BARALGIN M PILLS - 20 tablets
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1 tab. contains metamizole sodium 500 mg.
Mechanism of action
Baralgin M has an analgesic, antispasmodic, antipyretic, anti-inflammatory effect.
Indications and usage
Pain syndrome of low and medium intensity (headache and toothache, neuralgia, pain in radiculitis, osteochondrosis, arthritis, menalgia), smooth muscle spasms (renal colic, biliary colic, intestinal colic), feverish states in infectious and inflammatory diseases (as part of a combined therapy).
Hypersensitivity to pyrazolones (including Metamizolizopropylaminophenazone, propyphenazone and phenazone-containing agents, phenylbutazone). Acute hepatic porphyria, congenital deficiency of glucose – 6-phosphate dehydrogenase.
Contraindicated in the I and III trimesters of pregnancy. Use in the II trimester - only under strict medical indications. Breastfeeding is contraindicated within 48 hours after taking Baralgin M.
Dosage and administration
Baralgin M is taken orally, adults - 500-1000 mg 4 times a day. The maximum single dose - 1 g daily - 3 g.
Agranulocytosis, leukopenia, thrombocytopenia, a sharp drop in blood pressure, transient impaired kidney function (oliguria or anuria, proteinuria), interstitial nephritis, allergic and immunopathological reactions (urticarial eruptions on the skin, conjunctiva, mucous membranes in the nasal pharynx;, anaphylactic shock).
Baralgin M can not be mixed in the same syringe with other drugs. Removal with urine of one of the products of biotransformation may cause red staining of urine (has no clinical significance and disappears after withdrawal).
Simultaneous use of metamizol with other non-narcotic analgesics can lead to mutual enhancement of toxic effects. Tricyclic antidepressants, oral contraceptives, Allopurinol violate the metabolism of metamizol in the liver and increase its toxicity. Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effect of metamizol. Sedatives and tranquilizers enhance the analgesic effect of the drug. Simultaneous use with chlorpromazine or other phenothiazine derivatives may lead to the development of severe hyperthermia. Radiocontrast agents, colloidal blood substitutes and penicillin should not be used during treatment with metamizole.Metamizole, displacing oral hypoglycemic drugs, indirect anticoagulants, glucocorticosteroids and Indomethacin, increases their activity from a protein-related relationship. Myelotoxic drugs increase the hematotoxicity of the drug.
In case of overdose, consult a physician. The following symptoms may occur: nausea, vomiting, stomach pain, oliguria, hypothermia, low blood pressure, tachycardia, shortness of breath, tinnitus, drowsiness, delirium, impaired consciousness, acute agranulocytosis, hemorrhagic syndrome, acute renal or hepatic insufficiency, convulsions, paralysis of the respiratory muscles.
Treatment: induce vomiting, gastric lavage through a tube; saline laxatives, Activated carbon; conducting forced diuresis, hemodialysis; with the development of convulsive syndrome - intravenous administration of diazepam and high-speed barbiturates.
In the dark place at a temperature of 8-25 ° C.