ANALGIN PILLS 500MG

Mechanism of action

Analgesic, antispasmodic, antipyretic, anti-inflammatory. The mechanism is associated with inhibition of prostaglandin synthesis.

Indications and usage

Pain syndrome of low and medium intensity (headache and toothache, neuralgia, pain in radiculitis, osteochondrosis, arthritis, menalgia), smooth muscle spasms (renal colic, biliary colic, intestinal colic), feverish states in infectious and inflammatory diseases (as part of a combined therapy).

Contraindications

Hypersensitivity to pyrazolones (including Metamizolizopropylaminophenazone, propyphenazone and phenazone-containing agents, phenylbutazone). Acute hepatic porphyria, congenital deficiency of glucose-6-phosphate dehydrogenase.

Adverse reactions

Agranulocytosis, leukopenia, thrombocytopenia, a sharp drop in blood pressure, transient impaired kidney function (oliguria or anuria, proteinuria), interstitial nephritis, allergic and immunopathological reactions (urticarial eruptions on the skin, conjunctiva, mucous membranes in the nasal pharynx;, anaphylactic shock).

Drug Interactions

Reduces the concentration of cephalosporin in the blood, enhances the effect of alcohol.

For adults and adolescents over 15 years old is 500 mg. The maximum dose can reach 1000 mg up to 2-3 times per day. The maximum daily dose is 3000 mg. The duration of treatment is not more than 5 days when prescribed as an anesthetic and no more than 3 days as an antipyretic. pills should be taken with enough water. For children aged 2-3 years, 50-100 mg; 4-5 years - 100-200 mg; 6-7 years - 200 mg; 8-14 years - 250-300 mg 2-3 times a day. Children from 2 to 5 years old (weighing from 15 to 20 kg) - 1 supp. (200 mg) 1–4 times a day with an interval from 6 to 8 h.

Overdosage

Symptoms: nausea, vomiting, melena, epigastric pain, agranulocytosis, aplastic anemia, hemorrhagic diathesis, dizziness, tinnitus, clonic and tonic convulsions, cardiotoxic action, skin rash (bullous, petechial, cramping, cardiac toxicity, skin rashes (bullous, petechial, cramping, cardiotoxic action, skin rash (bullous, petechial, cramping, cardiac toxicity, skin rash) coma Treatment: gastric lavage, the appointment of laxatives and gastroprotective drugs, conducting forced diuresis, restoration of breathing, antishock measures, restoration of the BCC; if necessary, symptomatic therapy, with the development of seizures - in / in barbiturates and diazepam. There is no specific antidote.

Special notes

Removal with urine of one of the products of biotransformation may cause red staining of urine (has no clinical significance and disappears after withdrawal).

Storage conditions

Store in a dry, protected from light, out of reach of children, at room temperature no higher than 25 ° C.

Analgin