SPAZMALIN PILLS

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SPAZMALIN PILLS - 20tabs

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Indications

Pain in spasms of smooth muscles of internal organs:

- renal colic;

- biliary colic;

- Algomenorrhea.

Short-term symptomatic therapy for:

- arthralgia;

- neuralgia;

- ischialgia;

- myalgia.

To reduce pain after surgical and diagnostic interventions (as an aid).

Spasmalin in pill form is used for headaches and migraines.

Dosage and administration

Adults and teenagers over 15 years old inside the drug is usually prescribed 1-2 tab. 2-3 times / day. The maximum daily dose - 6 tab. Reception duration no more than 5 days. The increase in the daily dose of the drug or the duration of treatment is possible only under medical supervision.

For children the drug is prescribed according to strict indications; dose of the drug is set depending on age: age 6-8 years the recommended single dose is 1/2 tab., 9-12 years old - 3/4 tab., 13-15 years old - 1 tab. The multiplicity of reception - 2-3 times / day.

Tablets should be taken after meals.

Parenteral administration is usually used in emergency cases (renal or biliary colic) and in cases where ingestion is not possible (or absorption from the gastrointestinal tract is impaired).

For adults the average dose for iv administration is 2 ml. V / m injected 2-5 ml of solution 2-3 times / day; the maximum daily dose is 10 ml. The duration of treatment is not more than 5 days.

For children doses of Spasmalin for the / m or / in the introduction set depending on age.

Age

Recommended dose

3-11 months

0.1 ml

1-4 years

0.2 ml

5-7 years

0.4 ml

8-11 years old

0.5 ml

12-14 years old

0.8 ml

If necessary, re-introduction of the drug in the same doses.

Special care is required with the introduction of 2 ml of solution and more (the risk of a sharp decrease in blood pressure).

In / in the injection should be done slowly, in the position of the patient lying, under the control of blood pressure, heart rate and respiratory rate.

Spasmalin solution is incompatible in the same syringe with other drugs.

Adverse effects

Gastrointestinal: in isolated cases - a burning sensation in the epigastric region, dry mouth.

Cardiovascular: possible - lowering blood pressure, tachycardia, cyanosis.

Hemic and lymphatic: with prolonged use in some cases - thrombocytopenia, leukopenia, agranulocytosis.

From the side of the central nervous system: dizziness is possible; very rarely - accommodation paresis; in rare cases - headache.

Urogenital: rarely (usually with long-term use or when used in high doses) - impaired renal function, oliguria, anuria, proteinuria, interstitial nephritis, urine staining in red; very rarely - urinary retention.

Allergic reactions: sometimes - skin rash, itching; very rarely - anaphylactic shock; in some cases - malignant exudative erythema (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome); with predisposition to bronchospasm - provoking an attack.

Other: very rarely - decreased sweating.

At therapeutic doses, the drug is usually well tolerated.

Contraindications

- granulocytopenia,

- diseases of the hematopoietic system;

- severe liver dysfunction;

- pronounced renal dysfunction;

- deficiency of glucose-6-phosphate dehydrogenase;

- tachyarrhythmias;

- acute intermittent porphyria;

- angle-closure glaucoma;

- benign prostatic hyperplasia;

- intestinal obstruction;

- megacolon;

- collaptoid states;

- I term and the last 6 weeks of pregnancy;

- lactation (breastfeeding);

- children's age up to 3 months (or body weight less than 5 kg);

- hypersensitivity to the components of the drug, to pyrazolone derivatives (for example, to butadiene), to NSAIDs and antipyretic analgesics.

WITH caution and under the supervision of a physician should use the drug for violations of the function of the liver or kidneys, with a tendency to hypotension, bronchospasm. The question of the appointment of the drug to children and adolescents up to 15 years should be addressed individually.

Use during pregnancy and lactation

The drug is contraindicated for use in the first trimester and in the last 6 weeks of pregnancy. If necessary, the appointment of the drug during lactation should stop breastfeeding.

Application for violations of the liver

Contraindicated in marked disorders of the liver. WITH caution and under the supervision of a physician should use the drug for violations of liver function.

Application for violations of kidney function

Contraindicated in severe renal impairment. WITH caution and under the supervision of a physician should use the drug for violations of renal function.

Use in children

The drug is contraindicated in children up to 3 months (or body weight less than 5 kg).

The question of the appointment of the drug to children and adolescents up to 15 years should be addressed individually.

For children the drug is prescribed according to strict indications; dose of the drug is set depending on age: age 6-8 years the recommended single dose is 1/2 tab., 9-12 years old - 3/4 tab., 13-15 years old - 1 tab. The multiplicity of reception - 2-3 times / day.

For children doses of Spasmalin for the / m or / in the introduction set depending on age.

Age

Recommended dose

3-11 months

0.1 ml

1-4 years

0.2 ml

5-7 years

0.4 ml

8-11 years old

0.5 ml

12-14 years old

0.8 ml

Special notes

If you suspect agranulocytosis or in the presence of thrombocytopenia, you must stop taking the drug.

With long-term (more than a week) application of Spazmalin, control of the pattern of peripheral blood and the functional state of the liver is necessary.

During the period of use of the drug should not consume alcohol.

Influence on ability to drive motor transport and control mechanisms

During the period of use of the drug should not engage in potentially hazardous activities that require increased attention.

Overdosage

Symptoms: vomiting, lowering blood pressure, drowsiness, confusion, nausea, epigastric pain, abnormal liver and kidney function, convulsions.

Treatment: gastric lavage, the appointment of Activated carbon; if necessary, conduct symptomatic therapy.

Drug interaction

The simultaneous use of spasmalin with other non-opioid analgesics may result in mutual enhancement of effects.

With the simultaneous use of tricyclic antidepressants, oral contraceptives, Allopurinol violate the metabolism of metamizole sodium in the liver and increase its toxicity.

With the simultaneous use of barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the action of metamizole sodium.

With the simultaneous use of Spazmalin reduces the concentration of cyclosporine in the blood plasma.

With simultaneous use of sedatives and tranquilizers enhance the analgesic effect of Spazmalin.

With simultaneous use with histamine N blockers1-receptors, butyrophenones, phenothiazines, amantadine and quinidine may increase the m-cholinolytic effect of drugs.

When applied simultaneously with ethanol, mutual enhancement of effects is possible.

Terms and conditions of storage

The drug should be stored in a dark place, out of the reach of children at a temperature below 30 ° C.

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