No tax

IBUCLIN PILLS 100MG + 125MG - 20tabs



Security policy (edit with Customer reassurance module)


Delivery policy (edit with Customer reassurance module)


Return policy (edit with Customer reassurance module)

Dosage form

Dispersible pills (for children)


1 pill contains: Ibuprofen 100 mg, Paracetamol 125 mg;
excipients: microcrystalline cellulose 20 mg, corn starch 59.04 mg, lactose 5 mg, sodium carboxymethyl starch (type A) 30 mg, crimson dye (Ponso 4R) (E124) 0.2 mg, glycerol 2 mg, colloidal silicon dioxide 5 mg, orange flavoring DC 100 PH 1.6 mg, pineapple flavoring DC 106 PH 2.5 mg, peppermint leaf oil 0.66 mg, aspartame 10 mg, Magnesium stearate 1 mg, talc 3 mg.


20 pcs.

Mechanism of action

Ibuclin - a combined drug, the action of which is due to its constituent components.
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID), it has an analgesic, anti-inflammatory, antipyretic effect. Inhibiting cycloxygenase (COX) 1 and 2, violates the metabolism of arachidonic acid, reduces the number of prostaglandins (mediators of pain, inflammation and hyperthermic reaction), both in the focus of inflammation and in healthy tissues, suppresses the exudative and proliferative phases of inflammation.
Paracetamol - blocks COX indiscriminately, mainly in the central nervous system, has little effect on water-salt metabolism and the mucous membrane of the gastrointestinal tract (GIT). It has analgesic and antipyretic effects. In inflammatory tissues, peroxidases neutralize the effect of paracetamol on COX 1 and 2, which explains the low anti-inflammatory effect.
The effectiveness of the combination is higher than the individual components.

Indications and usage

Febrile syndrome
Pain syndrome of weak or moderate intensity of various etiologies: toothache, pain in sprains, sprains, fractures.
As an auxiliary drug for the treatment of pain and fever syndrome with sinusitis, tonsillitis, acute infectious and inflammatory diseases of the upper respiratory tract (pharyngitis, tracheitis, laryngitis).


Increased individual sensitivity to Ibuclin components (including other NSAIDs), gastric ulcer and duodenal ulcer in the acute phase, complete or incomplete combination of asthma, recurrent nasal polyposis and paranasal sinuses and intolerance to Acetylsalicylic acid or other NSAIDs (including, history), severe renal failure (CC less than 30 ml / min), damage to the optic nerve, genetic lack of glucose-6-phosphate dehydrogenase, diseases of the blood system, the period after prov Coronary artery bypass grafting, progressive kidney disease, severe liver failure or active liver disease, confirmed hyperkalemia, active Gastrointestinal bleeding, inflammatory bowel disease, children (up to 3 years).

Pregnancy and Breastfeeding

If necessary, the use of the drug Ibuclin during pregnancy and lactation (breastfeeding), should carefully weigh the expected benefits of therapy for the mother and the potential risk to the fetus or child.
If necessary, use in the first trimester of pregnancy should be excluded long-term use of the drug Ibuclin.
If necessary, short-term use of the drug Ibuclin during lactation, the termination of breastfeeding, usually not required.
In experimental studies, the embryotoxic, teratogenic and mutagenic effects of the components of the drug Ibuclin have not been established.

Dosage and administration

Ibuclin taken by mouth. Before use, the pill should be dissolved in 5 ml (1 teaspoon) of water. The daily dose of the drug is taken in 2-3 doses. The minimum time interval between taking the drug is 4 hours.
Children over 3 years old.
Single dose - 1 tablet. The daily dose depends on the age and weight of the child: 3-6 years (13-20 kg) - 3 pills per day; 6-12 years (20-40 kg) - up to 6 pills per day.
When violations of the kidneys or liver break between taking the drug should be at least 8 hours.
The drug should not be taken more than 5 days as an anesthetic and more than 3 days as an antipyretic without the supervision of a doctor.

Adverse reactions

At therapeutic doses, Ibuclin is usually well tolerated.
On the part of the digestive system: rarely - dyspeptic phenomena, with prolonged use in high doses - a hepatotoxic effect.
On the part of the hemopoietic system: rarely - thrombocytopenia, leukopenia, pancytopenia, neutropenia, agranulocytosis.
Allergic reactions: rarely - skin rash, itching, urticaria.
If you experience side effects, you should stop taking the drug and consult a doctor.

Special notes

The feasibility of using the drug as an antipyretic is solved in each case, depending on the severity, nature and tolerability of febrile syndrome.
Ibuprofen can mask the objective signs of infectious diseases, therefore, ibuprofen therapy in patients with infectious diseases should be administered with caution.
To reduce the risk of adverse events from the gastrointestinal tract, use the minimum effective dose of the shortest possible course.

With simultaneous use of the drug Ibuclin with drugs may develop various effects of the interaction.
Prolonged combined use with paracetamol increases the risk of nephrotoxic effects.
The combination with ethanol, glucocorticosteroids, corticotropin increases the risk of erosive and ulcerative lesions of the gastrointestinal tract.
Ibuprofen enhances the effect of direct (heparin) and indirect (coumarin and indandion derivatives) anticoagulants, thrombolytic agents (alteplase, anistreplaza, streptokinase, urokinase), antiplatelet agents, colchicine - the risk of hemorrhagic complications increases.
Enhances the hypoglycemic effect of insulin and oral hypoglycemic drugs.
Weakens the effects of antihypertensive drugs and diuretics (by inhibiting the synthesis of renal prostaglandins).
Increases blood concentration of Digoxin, lithium preparations and Methotrexate.
Caffeine enhances the analgesic effect of ibuprofen.
Cyclosporine and gold medications increase nephrotoxicity.
Cefamundol, cefoperazone, cefotetan, valproic acid, plykamycin increase the incidence of hypoprothrombinemia.
Antacids and colestyramine reduce the absorption of the drug.
Myelotoxic drugs contribute to the hematotoxicity of the drug.


Symptoms: gastrointestinal disorders (abdominal pain, diarrhea, nausea, vomiting, anorexia, pain in the epigastric region), an increase in prothrombin time, bleeding after 12-48 hours, lethargy, drowsiness, depression, headache, tinnitus, disturbance consciousness, cardiac arrhythmias, lowering blood pressure, manifestations of hepato-and nephrotoxicity, convulsions, the development of hepatonecrosis is possible.
Treatment: gastric lavage for the first 4 hours; alkaline drink, forced diuresis; activated charcoal orally, the introduction of SH-group donators and precursors of glutathione-methionine synthesis 8–9 hours after an overdose, and N-acetylcysteine ​​orally or intravenously — after 12 hours, antacids; hemodialysis; symptomatic therapy. The need for additional therapeutic measures (further introduction of methionine, intravenous administration of N-acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as on the time that has passed since taking it.

Storage conditions

In a dry, dark place and out of reach of children, at a temperature not higher than 25 ° C.


41 Items