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Indications and usage

Pain and limited mobility in degenerative and traumatic changes in the knee and other synovial joints.

Mechanism of action

Hyaluronic acid (HA) is a natural polymer that provides the viscoelastic properties of synovial fluid. In a normal joint, it has a high concentration on the surface layer of the articular cartilage, as well as on the surface layers of the synovial membrane. In synovial fluid, HAs act as a lubricant and shock absorber, an energy-accumulating agent between cartilage opposite each other, a semi-permeable barrier that regulates metabolic exchanges between cartilage and synovial fluid, an agent that controls cell movement and a viscoelastic screen around synoviocytes and adjacent nerve endings.
A healthy synovial joint is in equilibrium or homeostasis. GC constantly moves in the joint cavity, but its concentration and molecular weight profile remain constant. OSTENIL contains a special fraction of high-purity sodium hyaluronate obtained by bacterial fermentation. The product does not contain animal proteins, which reduces the risk of an allergic reaction, and a narrow molecular weight range helps to ensure that there are no lungs that cause inflammation and hyaluronic acid fragments.

Depending on the size of the joint, inject up to 2 ml of OSTENIL into the joint cavity once a week for 3 to 5 weeks in a row. Several joints can be treated at the same time.

Information about the incompatibility of OSTENIL with other solutions for intra-articular use at this time is missing.

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