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Mechanism of action

Combined drug with antithrombotic, anti-inflammatory and improves tissue regeneration action for external use.
Heparin is a direct acting anticoagulant. When applied topically, Heparin prevents the formation of blood clots, has anti-edema and anti-inflammatory effects, improves local blood flow.
Allantoin has anti-inflammatory effects, stimulates the metabolic processes in tissues and promotes cell proliferation.
Dexpantenol improves the absorption of heparin, stimulates the radius and epithelization of tissue.

After local application to the skin, heparin penetrates relatively quickly through the epidermis and accumulates in the upper layers of the skin. Actively bound to skin proteins. It is released slowly from the tissue with a period of about 1 h. The pharmacological effect is concentrated from 10 U / ml in the epidermis and 0.6 U / ml in the skin, respectively.

Indications and usage

- thrombosis;
- thrombophlebitis;
- varicose veins of the leg;
- ulcers of the leg with local circulatory disorders;
- sports injuries;
- tendovaginitis;
- local inflammatory (non-infectious) processes of the skin and soft tissues (only for ointment);
- infiltration (lymphangitis, avenging) (only for ointment).

On the affected areas 1-3 times / day apply a column of ointment or gel with a length of 5 cm.
At leg vein disease without thrombosis smear It is applied with light mass movements along the direction from bottom to top, it is recommended to apply a single dose not in full, but in separate portions.
At thrombosis and thrombophlebitis ointment should be applied in the form of dressings, do not rub or massage.
At varicose ulcers The ointment is applied around the edges of the ulcer in the form of a ring about 4 cm wide.
Gel apply only on intact skin with a thin layer, rubbing with light massaging movements from the bottom up.
In case of using a gel with thrombosis and thrombophlebitis Mass propagation is also not recommended.

Adverse reactions

Local reactions: in some cases - erythema, skin rash.
Allergic reactions: in some cases - urticaria, angioedema.


- for the second time infected affected skin surfaces;
- open wounds (including bleeding ulcer of the leg);
- Hypersensitivity to the drug.

Pregnancy and breastfeeding

Data on the possibility of using the drug Gepatrombin during pregnancy and lactation is not provided.

The essential oils included in the composition of other ingredients of the gel have antimicrobial and analgesic effects.


Data on drug overdose Gepatrombin not provided.

Drug Interactions

Data on drug interactions of the drug Gepatrombin not provided.

Storage conditions

The drug should be stored at a temperature of 15 ° to 25 ° C. Shelf life - 3 years.

The drug is approved for use as a means of OTC.

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