SUPRASTIN AMPOULES 2% 1 ML
SUPRASTIN 5 AMPOULES 2% 1 ML
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Active ingredient and dosage form
pills: 1 pill contains chloropyramine hydrochloride 25 mg;
Excipients: lactose, starch, talc, sodium amylopectin, gelatin, stearic acid;
in vials of 20; in a carton pack 1 bottle
or in a blister, 10 pcs.; in a pack of cardboard 2 blisters.
Suprastin injection: 1 ampoule contains chloropyramine hydrochloride 20 mg;
in 1 ml ampoules; in a pack of cardboard 5 ampoules.
Mechanism of action
Suprastin - histamine H blocker1-receptors, a derivative of ethylene diamine. Prevents the development and facilitates the course of allergic reactions. It has a moderate sedative and pronounced antipruritic effect. It has peripheral anticholinergic activity, moderate antispasmodic properties.
Indications and usage
Allergic diseases (including urticaria, serum sickness, pollinosis, or hay fever, rhinitis, conjunctivitis); anaphylactic shock and angioedema; skin diseases (including contact dermatitis, acute and chronic eczema, neurodermatitis, toxicoderma); prevention and treatment of allergic and pseudo-allergic reactions to the use of drugs and diagnostic products; itching and insect bites; SARS.
Glaucoma (for parenteral administration), benign prostatic hyperplasia, urinary retention (for parenteral administration); simultaneous administration of MAO inhibitors (for parenteral administration); gastric ulcer in the acute phase (for parenteral administration); acute attack of bronchial asthma; pregnancy; lactation (breastfeeding); the drug is not prescribed to newborns under the age of 1 month; hypersensitivity to the drug or other derivatives of ethylenediamine.
Dosage and administration
Assign inside, in / m and / in.
For adults appoint 25 mg (1 tab.) 3-4 times a day (75-100 mg / day).
Children aged 1-12 months appoint 1/4 tab. (6.25 mg) 2-3 times a day (in the form of pounded to a powder, together with baby food); 2-6 years - 1/3 tab. (8.3 mg) 2-3 times a day; 7-14 years old- 1/2 tab. (12.5 mg) 3 times a day.
pills should be taken after meals.
AT severe and acute cases of allergic and Anaphylactic reactions therapy can begin with parenteral administration of the drug. At the beginning of the treatment, Suprastin is administered intravenously, then intramuscularly, and at the end it is taken to take the drug by mouth. In anaphylactic shock, the drug should be administered after the administration of adrenaline.
For adults the drug is administered intramuscularly or intravenously in a dose of 20-40 mg (1-2 ml of solution).
Initial dose of solution for injection for children from 1 month to 1 year makes 5 mg (0.25 ml of solution); from 1 year to 6 years - 10 mg (0.5 ml of solution); from 6 to 14 years - 10-20 mg (0.5-1 ml of solution). Further therapy and / or increase in dose is largely determined by the presence of side effects.The maximum daily dose is 2 mg / kg body weight.
From the side of the central nervous system: possible lethargy, drowsiness, weakness, light tremor, dizziness. Children may have some stimulating effect on the central nervous system, manifested by anxiety, increased irritability, insomnia.
Gastrointestinal: possible dry mouth, nausea, vomiting, diarrhea, or constipation.
Cardiovascular: rarely - lowering blood pressure (more often in elderly patients), tachycardia, arrhythmia.
Allergic reactions: possible skin rash, itching.
Other: rarely, difficulty urinating.
The drug should be used with caution in elderly patients, with a lack of liver function and / or heart disease. With extreme caution should be prescribed the drug inside with angle-closure glaucoma, in patients with urinary retention and prostatic hypertrophy.
When taken at night, the drug may increase the symptoms of reflux esophagitis.
With caution, Suprastin should be prescribed simultaneously with sedatives, tranquilizers, analgesics, MAO inhibitors, tricyclic antidepressants, atropine and / or sympatholytics.
During treatment, you should exclude the use of alcoholic beverages.
Influence on ability to drive motor transport and control mechanisms
In the initial, individually determined period of Suprastin use, driving of vehicles and engaging in other potentially hazardous activities requiring psychomotor speed is not allowed.In the process of further treatment, the degree of restriction is determined depending on the individual tolerance of the drug.
With simultaneous use of Suprastin enhances the effects of anesthetics, hypnotics, tranquilizers, analgesics, MAO inhibitors, tricyclic antidepressants, atropine and sympatholytics.
With simultaneous use of Suprastin and caffeine or phenamine, a decrease or elimination of the suppressive effect of Suprastin on the CNS is noted.
Store at room temperature (not exceeding 25 ° C).
Shelf life: 5 years.