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Active ingredient and dosage form

Vaginal suppositories:
ketoconazole 400 mg;
Excipients: butyloxyanisole, polyethylene oxide 1500, polyethylene oxide 400;
5 or 10 pcs. packaged.

Mechanism of action

Livarol is an antifungal drug from the group of imidazoldioxolane derivatives for topical use. It has fungicidal and fungostatic effects on dermatophytes (Trichophyton spp., Epidermophyton floccosum, Microsporum spp.) And yeast (Candida spp., Pityrosporum spp.). The mechanism of action is to inhibit the biosynthesis of ergosterol and change the lipid composition of the membrane of fungi.
The drug is active against staphylococci and streptococci.

Indications and usage

Treatment of acute and chronic recurrent mycosis of the vagina.
Preventing the occurrence of fungal infections of the vagina with low resistance of the body and against the background of treatment with antibacterial agents and other drugs that violate the normal vaginal microflora.


Hypersensitivity to the drug.

Carefully use the drug during pregnancy and lactation.

Dosage and administration

Livarol is injected deep into the vagina in the supine position 1 time per day for 3-5 days depending on the course of the disease, and if necessary, repeat the treatment.

Adverse reactions

Allergic reactions (itching, burning) at the injection site, in rare cases nausea, dizziness.

Drug interactions

With simultaneous use of rifampicin and isoniazid, the concentration of Ketoconazole in plasma decreases.
With simultaneous use with cyclosporine, indirect anticoagulants and methylprednisolone, ketoconazole may increase the concentration of the latter in plasma.

Special notes

Contact with latex preparations (contraceptive diaphragms, condoms) should be avoided.

Storage conditions

Keep out of the reach of children, dry, dark place at temperatures not above 25 ° C.


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