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Active ingredient and dosage form

Cordaflex - tablets, film-coated: 1 tab. contains Nifedipine 10 and 20 mg, excipients: polyvinyl butyral; Magnesium stearate; talc; hydroxypropylcellulose; croscarmellose sodium; lactose monohydrate; MCC; titanium dioxide; iron oxide yellow; hypromellose; Packed in 30, 60 and 100 pcs.

Mechanism of action

Cordaflex has an antianginal, hypotensive effect.

Indications and usage

For Cordaflex pills of 10 mg: arterial hypertension, including hypertensive crises; IHD: stable stenocardia (exertional angina), vasospastic stenocardia (Prinzmetal's stenocardia). prophylaxis, in some cases, relief of attacks in various forms of angina, including variant - Prinzmetal's stenocardia; Raynaud's syndrome.


Hypersensitivity, acute myocardial infarction (first 8 days), cardiogenic shock, severe aortic stenosis, heart failure in the decompensation stage, severe arterial hypotension, tachycardia, pregnancy, breast-feeding.


Since the cardiovascular system and blood (hematopoiesis, hemostasis: often (at the beginning of treatment) - hyperemia of the person with a sensation of heat, palpitations, tachycardia; rarely - hypotension (up to fainting), pain similar to angina, very rarely - anemia, leukopenia, thrombocytopenia, thrombocytopenic purpura.

On the part of the nervous system and sensory organs: at the beginning of treatment - dizziness, headache, rarely - stupidity, very rarely - a change in visual perception, impaired sensitivity in the arms and legs.

On the part of the digestive tract organs: often - constipation, rarely - nausea, diarrhea, very rarely - gingival hyperplasia (with long-term treatment), increased activity of hepatic transaminases.

On the part of the respiratory system: very rarely - bronchospasm.

On the part of the musculoskeletal system: very rarely - myalgia, tremor.

Allergic reactions: itching, urticaria, exanthema, rarely - exfoliative dermatitis.

Other: often (at the beginning of treatment) - swelling and redness of the arms and legs, very rarely - photodermatitis, hyperglycemia, gynecomastia (in elderly patients), burning sensation at the injection site (with a / in the introduction).

Dosage and administration

Cordaflex accept inside.

Cordaflex 10 mg pills should be swallowed whole before meals, without chewing, with a small amount of water.

The dosage regimen is set individually, depending on the severity of the disease and the response of the patient to the therapy. The initial dose - 1 tab. (10 mg) 3 times a day.If necessary, the dose can be increased to table 2. (20 mg) - 1-2 times a day. Between two doses of the drug should take at least 2 hours. The maximum daily dose is 40 mg.

Tablets prolonged action Cordaflex 20 mg, taken regardless of the meal, with a small amount of water.

The drug has a large therapeutic dosing range, which is set individually depending on the severity of the disease and the patient's response to therapy.

A usual initial dose - 1 tab. (20 mg) 2 times a day with an interval of 12 hours. If necessary, the dose of the drug is titrated to obtain the desired clinical effect. For long-term maintenance therapy, it is usually enough to take 1-2 tablets. (20-40 mg) 2 times a day. The maximum daily dose should not exceed 120 mg.

Storage conditions

In a dry, dark place at a temperature of no higher than 25 ° C. Shelf life - 4 years.

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