MARVELON PILLS

Dosage form

Pills

Composition

1 pill contains: desogestrel 0.15 mg, ethinyl estradiol 0.03 mg.

Excipients: potato starch, povidone, stearic acid, colloidal anhydrous silicon oxide, A-tocopherol, lactose monohydrate.

Packing

In the blister 21 tablets. In packing 1 blister.

Mechanism of action

Marvelon is a contraceptive (estrogen + progestogen). Marvelon is a combined oral contraceptive. Each pill contains a small amount of two different female hormones - desogestrel (progestogen) and ethinyl estradiol (estrogen).

Due to small amounts of hormones, Marvelone is referred to as low-dose oral contraceptives. Since all the pills in a pack contain the same amount of the same hormones, Marvelon refers to monophasic combined oral contraceptives.

While taking the drug, menstruation becomes less plentiful and painful.
Women taking birth control pills are less likely to have anemia, certain diseases of the uterus, ovaries, and mammary glands.
It has a beneficial effect on the skin, especially improving its condition in case of acne vulgaris.
After stopping the drug, the ability to conceive is quickly restored.

Indications and usage

Contraception (pregnancy prevention).

Contraindications

- Thrombosis (venous or arterial) currently or in history (including deep vein thrombosis, pulmonary embolism, myocardial infarction, stroke).
- Present or in history of possible clinical manifestations of thrombosis (including ischemic disease or angina).
- Diabetes mellitus with vascular lesions.
- The presence of severe or multiple risk factors for venous or arterial thrombosis (see “Side Effects”).
- Present or current history of severe liver disease (if liver function indicators have not returned to normal).
- Present or current history of liver tumors (benign and malignant).
- Established or suspected hormone-dependent malignant tumor of the genitals or mammary glands.
- Vaginal bleeding of unknown etiology.
- Established or suspected pregnancy, lactation.
- Hypersensitivity to any of the components of the drug.
- Migraine with focal neurological symptoms.
- Hypertriglyceridemia.

If the drug is used against the background of one of the following conditions, you may need to be monitored regularly by a doctor. Before you start taking the drug, be sure to tell your doctor about the following conditions / diseases:

- Smoking.
- Migraine.
- Epilepsy.
- Diabetes.
- Overweight.
- High blood pressure.
- Heart valve disease or heart rhythm disorder.
- Inflammation of the veins (superficial thrombophlebitis).
- Phlebeurysm.
- The next of kin had a thrombosis, myocardial infarction, or stroke.
- You or your next of kin have a high or high blood cholesterol or triglyceride level.
- One of the closest relatives had breast cancer.
- Disease of the liver or gallbladder.
- Crohn's disease or ulcerative colitis (chronic inflammatory bowel disease).
- Systemic lupus erythematosus.
- Hemolytic uremic syndrome (bleeding disorder causing renal failure).
- Sickle cell anemia.
- There is or was chloasma (yellow-brown patches of skin pigmentation, mainly on the face). In this case, prolonged exposure to sunlight or ultraviolet radiation should be avoided.

Pregnancy and Breastfeeding

Contraindicated during established or intended pregnancy and lactation.

Dosage and administration

The package contains 21 tablets. Each pill indicates on which day of the week it should be taken. pills are taken orally, every day, at about the same time, with a small amount of water. Follow the direction indicated by the arrows until all pills are taken.Do not take pills for the next 7 days. During this period, menstruation should begin (bleeding after discontinuation of the drug). Typically, menstruation begins 2-3 days after taking the last pill. On the 8th day, even if your period continues, start taking the pills from the next pack.

How to start taking the drug Marvelon: eIf you have not used oral contraceptives during the last month: start taking Marvelon on the first day of the menstrual cycle (on the first day of your period). Take a pill that indicates this day of the week, then continue to take one pill per day in order. You can also start taking Marvelon for 2-5 days after the start of the menstrual cycle, but in this case you need to use additional non-trivial methods of contraception during the first 7 days of taking the pills in the first cycle.
When switching from other combination pills: You can start taking Marvelon the next day after taking the last pill of the drug you are using without any interruption. If the contraceptive package also contains inactive pills (without hormones), you can start taking Marvelon the next day after taking the last pill with hormones. You can start taking Marvelon pills and later, but no later than the next day after a break in taking the pills (or the next day after taking the last inactive pill).
When switching from progestogen-only pills (mini-pili): You can stop taking “mini-drank” any day and start taking Marvelon the next day at the same time. However, during the first seven days of taking Marvelon tablets, you must use additional methods of contraception.
When switching from an injection or implant: Start using Marvelon on the day when there should be the next injection or on the day of the implant removal. During the first seven days of taking Marvelon tablets, you must use additional methods of contraception.
After giving birth: It is recommended to wait for the onset of the first normal menstruation before starting to take Marvelon. If you are breastfeeding, you should consult a doctor.
After miscarriage or abortion: follow the doctor's recommendations.

If you want to stop taking Marvelon: you can do this anytime you want. If you stop taking the drug because you want to get pregnant, then before you try to conceive a child, it is usually recommended to wait until the first natural menstruation occurs. This will allow you to predict the date of birth of the child.

What to do if you miss the next drug intake: if you are late with taking the next pill in less than 12 hours, the effectiveness of the drug is preserved. Take the missed pill as soon as you remember, and take the next pill at the usual time.If you are late with taking a regular pill for more than 12 hours, then the effectiveness of the drug may be reduced. The more pills you missed, the higher the risk of reducing contraceptive effectiveness. Especially high risk of pregnancy, if you miss the pills at the beginning or at the end of the pack. Therefore, you must follow the rules below. More than one missed pill in a pack - consult a doctor.
1 missed pill in the 1st week: Take the missed pills as soon as you remember (even if you have to take two pills at the same time) and take the following pills at the usual time. Use additional contraceptive methods for the next seven days. If you had sexual intercourse during the week before skipping the pill, then pregnancy may occur. Report this to your doctor immediately.

1 missed pill in the 2nd week: Take the missed pills as soon as you remember (even if you have to take two pills at the same time) and take the following pills at the usual time. The effectiveness of the drug is maintained, so additional methods of contraception are not required.

1 missed pill in the 3rd week: You can choose one of the following schemes without resorting to additional contraceptive measures:
Take the missed pills as soon as you remember (even if you have to take two pills at the same time) and take the following pills at the usual time. Start the next package as soon as the current one ends, without taking a break in taking the drug.Bleeding with the cancellation may not be until the end of the second pack of the drug, but there may be spotting or unexpectedly abundant bleeding on the days of taking the pills.
Stop taking the pills from the currently used pack, take a break of 7 days or less (given the day you missed the pill) and start taking the pills from the next pack. In this case, you can always start taking pills from the next pack on the same day of the week, as usual.

Recommendations for vomiting or diarrhea: If vomiting or diarrhea occurs within 3–4 hours after taking the drug, absorption may not be complete. In this case, you should use the recommendations regarding the admission of the next drug intake.

If you want to delay the onset of menstruation: You can postpone your period if you start taking the pills from the next pack as soon as the previous one has finished (without a break). You can take the pills from the next pack until they run out. If you want to start your period, stop taking the pills. When you take pills from the second pack, you may experience unexpectedly heavy bleeding or spotting. Taking the pills from the next pack should start after a 7-day break.

If you want to change the day of the beginning of menstruation: when using the drug in accordance with the recommendations, menstruation begins on the same day every 4 weeks. If you want to change the day you start menstruating, take a shorter next break in the pill.For example, if menstruation usually begins on Friday, and you want it to start on Tuesday (three days earlier), you should start taking the pills from the next pack 3 days earlier than usual. If you take a too short break in taking the pill (for example, 3 days or less), then you may not have any bleeding during the break. While taking the pills from the next pack, there may be spotting or unusually heavy bleeding.

If you have an unexpected bleeding: as with other oral contraceptives, irregular vaginal bleeding (spotting or sudden vaginal bleeding) between menses may occur during the first few months. The drug in this case should be continued as usual. The appearance of intermenstrual bleeding during the first three months of administration does not mean that the contraceptive effect is reduced or that the drug does not suit you. Irregular vaginal bleeding usually stops after your body adapts to the drug (usually after three cycles of taking the pills). If the bleeding continues, become abundant, consult a doctor.

If you have no menstruation: if you took all the pills in a timely manner, you did not have vomiting or diarrhea, you did not take other medicines, then it is unlikely that you are pregnant. Keep taking marvelon as usual.If you did not have menstruation twice in a row, you may be pregnant. Do not start a new package until the doctor excludes pregnancy.

Side effects can occur in the first few months of using the drug and usually decrease with time.

Headache, gastralgi, nausea, vomiting, soreness and engorgement of the mammary glands, increased body mass, impaired glucose tolerance, fluid retention in the body, changes in libidus, decreased mood, edema, skin rash, erythema nodosum, conjunctivitis, unpleasant sensations when worn contact lines, thrombophlebitis, thromboembolism (may manifest as impaired perception: impaired vision, loss of hearing), generalized itching, cholestatic jaundice, cholelithiasis, increased blood pressure, intermenstrual bleeding, vaginal changes th secretion, the development of vaginal candidiasis is possible, with prolonged use (extremely rare) - chloasma, hepatocellular adenoma.

If you are taking birth control pills, you need to undergo regular annual checkups.

Contact your doctor immediately if: you notice any changes in health status (see sections "Contraindications", "Side Effects"); you have a lump in the breast; going to take other medicines; You have to stay in bed (during illness, after injury), or you will have surgery; you have very intense or prolonged vaginal bleeding; You missed a pill in the first week, and you had sexual intercourse seven days before; You suspect that you are pregnant.

Stop taking the drug and consult a doctor immediately if you notice possible signs of thrombosis: unusual cough; severe pain behind the sternum, which can be given to the left hand; shortness of breath; unusual, severe pain, or prolonged headache or migraine attack; partial or complete loss of vision or double vision; speech impairment or loss of speech; sudden change in hearing, smell, or taste; dizziness or fainting; weakness or loss of sensation in any part of the body; severe abdominal pain; severe pain or swelling of the leg.

Interaction with certain medications can lead to heavy bleeding and ineffectiveness of oral contraceptives. Such cases were observed when taking hydantoins, barbiturates, primidone, Carbamazepine , rifampicin, isoniazid; they are possible with the appointment of oxcarbamazepine, topiramate , felbamate and Griseofulvin . A decrease in the effectiveness of oral contraceptives was also observed when taking certain antibiotics, such as ampicillin, Tetracycline , neomycin, penicillins, chloramphenicol, as well as Activated carbon , laxatives.

Marvelone reduces the effectiveness of oral anticoagulants, anxiolytics (diazepam), tricyclic antidepressants, theophylline, caffeine, hypoglycemic drugs, clofibrate, glucocorticosteroids.

Always tell the doctor who prescribes birth control pills which medicines you already use.If your doctor prescribes other medications for you, let him know that you are taking Marvelon.

The serious consequences of taking a large number of Marvelon pills have not been reported.

Symptoms: If you take several pills at once, you may experience nausea, vomiting, vaginal bleeding.
Treatment: If you find that a child has swallowed a pill, consult a doctor.

Store at a temperature of 2-30 ° C. Protect from light and moisture.

3 years.

Marvelon