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COSMETIC BRANDS
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COSMETIC BRANDS
EMANERA CAPSULES 20MG
EMANERA CAPSULES 20MG - 14 pcs
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Indications and usage
Gastroesophageal reflux disease: erosive reflux esophagitis (treatment), prevention of relapse in patients with cured esophagitis, symptomatic treatment of GERD.
In combination therapy: Helicobacter pylori eradication, duodenal ulcer associated with Helicobacter pylori, prevention of peptic ulcer recurrence in patients with Helicobacter pylori associated ulcer.
Contraindications
Lactation period, hypersensitivity to esomepromazole.
Dosage and administration
Is ingested. The dose is 20-40 mg 1 time / day. The duration of treatment depends on the indications, treatment regimen, effectiveness.
In severe liver failure, the maximum dose is 20 mg / day.
Adverse Effects
Often: headache, abdominal pain, diarrhea, flatulence, nausea, vomiting, constipation.
Seldom: dermatitis, pruritus, urticaria, dizziness, dry mouth.
If there are symptoms such as significant spontaneous weight loss, frequent vomiting, dysphagia, vomiting of blood or melena, as well as the presence (or suspicion) of a stomach ulcer, the possibility of malignant neoplasm should be excluded, since treatment with esomeprazole can lead to smoothing symptoms and, thus, delay the formulation of the correct diagnosis.
With prolonged therapy, the patient’s condition should be monitored regularly.
During treatment with proton pump inhibitors, gastrin plasma levels rise as a result of reduced intragastric secretion of hydrochloric acid. In patients taking proton pump inhibitors for a long time, the formation of glandular cysts in the stomach is more often noted. These phenomena are due to physiological changes as a result of inhibition of the secretion of hydrochloric acid.
It is believed that with simultaneous use may increase concentrations in the blood plasma and enhance the effects of imipramine, clomipramine, citalopram.
It is believed that with simultaneous use, it is possible to reduce plasma concentrations and the clinical efficacy of itraconazole and Ketoconazole.
With simultaneous use with Clarithromycin, a case of a significant increase in the AUC of esomeprazole due to the inhibition of its metabolism under the influence of clarithromycin has been described.
With simultaneous use may increase concentrations in the blood plasma of diazepam and phenytoin, which, apparently, has no clinical significance.
Emanera