RENNIE CHEWABLE PILLS ORANGE

Trade name of the drug

Rennie

Grouping name

Calcium carbonate + Magnesium carbonate.

Dosage Form

Chewable pills [orange].

Description

White with a creamy shade square pills with concave surfaces, engraved with "RENNIE" on both sides, with the smell of orange.

Composition

1 pill contains

Active ingredients: calcium carbonate 680 mg, magnesium carbonate basic (magnesium hydroxycarbonate) 80 mg.

Excipients: sucrose 475 mg, pregelatinized corn starch 20 mg, potato starch 13 mg, talc 33.14 mg, magnesium stearate 10.66 mg, liquid paraffin 5 mg, orange flavoring (orange oil, maltodextrin, purified water) 35.2 mg, sodium saccharinate 2 mg.

Pharmacotherapeutic group

Antacid.

Pharmacological properties

Pharmacodynamics. Antacid preparation of local action. Rennie pill contains antacid substances - Calcium carbonate and magnesium carbonate, which provide fast and long-lasting neutralization of excess hydrochloric acid of the gastric juice, thereby has a protective effect on the gastric mucosa. Achieving a positive effect within 3-5 minutes due to the good solubility of pills and high calcium content.

Pharmacokinetics. As a result of Rennie's interaction with gastric juice, soluble calcium and magnesium salts are formed in the stomach. The level of absorption of calcium and magnesium from these compounds depends on the dose of the drug. The maximum level of absorption is 10% calcium and 15-20% magnesium. A small amount of absorbed calcium and magnesium is excreted through the kidneys. When kidney damage, plasma and calcium concentrations may increase. In the intestine of soluble salts are formed insoluble compounds that are excreted in the feces.

Indications for use

Symptoms associated with increased acidity of gastric juice and reflux esophagitis: heartburn, sour eructation, recurrent pain in the stomach, feeling of fullness or heaviness in the epigastric region, dyspepsia (including caused by error in diet, medication, abuse of alcohol, coffee nicotine), dyspepsia pregnant.

Contraindications

Severe renal failure, hypercalcemia, hypophosphatemia, nephrocalcinosis, hypersensitivity to the drug, children up to 12 years of age.

Use during pregnancy and lactation

When used in recommended doses, the drug does not pose a danger to the fetus or child.

Dosage and administration

Inside

Adults and children over 12 years old: unless otherwise recommended by a doctor, chew 1-2 pills when symptoms appear or chew in the mouth until completely dissolved. If necessary, you can repeat the drug after 2 hours.

The maximum daily dose is 11 tablets.

Side effects

If the recommended doses are taken, the drug is well tolerated, however, in very rare cases, allergic reactions are possible: rash, angioedema, and Anaphylactic reactions. Prolonged use of the drug in high doses in patients with impaired renal function can cause hypermagneemia, hypercalcemia.

Overdose

Prolonged use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which can manifest nausea, vomiting, muscle weakness. In this case, you should cancel the drug and immediately consult a doctor.

Interaction with other drugs

Changes in the acidity of gastric juice, during the use of antacids, can lead to a decrease in the rate and extent of absorption of other drugs, while taking it, so drugs should be taken 1-2 hours before or after taking antacids.

Tetracycline antibiotics, fluoroquinolones, cardiac glycosides, levothyroxine, iron preparations, fluorides, phosphates - while the use of antacids reduces the absorption of these drugs.

Thiazide diuretics - when taken concurrently with antacids, the concentration of calcium in blood serum should be regularly monitored.

special instructions

In the appointment of the drug to patients with impaired renal function should regularly monitor the concentration of magnesium,phosphorus and calcium in serum.

Patients with impaired renal function is not recommended for a long time to take the drug in high doses.

The use of Rennie in high doses may increase the risk of kidney stones.

The instruction to patients with diabetes mellitus: 1 pill Renny contains 475 mg of sucrose.

If the use of the drug is ineffective, you should consult your doctor for advice.

Influence on ability to steer the car and moving mechanisms

Does not affect.

Release form

Chewable pills [orange]. On 6 pills in a thermowelled aluminum / PVC blister. On 2, 4, 6, 8 and 16 blisters together with the application instruction in a cardboard pack.

On 12 pills in a thermowelled aluminum / PVC blister. On 1, 2, 3, 4 and 8 blisters together with the application instruction in a cardboard pack.

Storage conditions

At a temperature not higher than 25 ° С. Keep out of the reach of children.

Shelf life

3 years. Do not use after expiration date.

Vacation conditions

Over the counter.