ESSENTIALE N AMPOULE 5ML

Dosage form

Solution for IV injection

Composition

5 ml (1 amp.) Contains “essential” phospholipids 250 mg;
Excipients: benzyl alcohol - 45 mg; deoxycholic acid - 115 mg; sodium chloride - 12 mg; sodium hydroxide - 11.5 mg; Riboflavin - 0.5 mg; α-tocopherol - 0.75 mg; ethanol - 16.304 mg; water for injection - 4543,68 mg

Packaging

5 pieces.

Mechanism of action

Essentiale N - hepatoprotector. Active substances - "essential" phospholipids (substance EPL) - are the main elements in the structure of the cell wall and liver cell organelles. EPL contains naturally occurring diglyceride esters of choline phosphoric acid, an extract from soy beans with a high content of unsaturated fatty acids, mainly linoleic (about 70%), linolenic and oleic acids.
When the liver metabolism is disturbed, Essentiale N ensures the supply of ready-to-absorb high-energy "essential" phospholipids, which are ideally combined with endogenous phospholipids by chemical structure. They mainly penetrate the liver cells, invading their membranes.
Essentiale N normalizes liver function and enzyme activity of liver cells, reduces the level of liver energy expenditure, promotes liver cell regeneration, converts neutral fats and cholesterol into forms that facilitate their metabolism, stabilize the physico-chemical properties of bile.

Indications and usage

- fatty degeneration of the liver of various etiologies (including diabetes mellitus);
- acute and chronic hepatitis;
- cirrhosis of the liver;
- necrosis of liver cells;
- hepatic coma and precoma;
- toxic liver damage;
- pregnancy toxicosis;
- pre- and postoperative treatment, especially during operations in the area of ​​the hepatobiliary zone;
- psoriasis (as an adjuvant therapy);
- radiation syndrome.

Contraindications

- hypersensitivity to the drug.
Solution for IV injection can not be used to treat newborns and premature babies.

Dosage and administration

250-500 mg (1-2 amp. Essentiale N) are prescribed intravenously (slowly), in severe cases - 500 mg-1 g (2-4 amp.) Per day. The contents of two ampoules can be administered simultaneously. Use only clear solution. Avoid mixed injections.

It is recommended to supplement parenteral administration with oral administration of the drug as soon as possible. In such cases, the initial dose for oral administration - 2 capsules 3 times / day, supporting - 1 capsule 3 times / day.

Adverse reactions

Gastrointestinal: when using the solution in high doses rarely - diarrhea; when using capsules rarely - a feeling of discomfort in the abdomen.
Other: when using capsules rarely - allergic reactions.

Storage conditions

Store at a temperature not exceeding 8 ° C.