CORILIP RECTAL CANDLES

Dosage form

Rectal Candles

Composition

1 rectal suppository contains: cocarboxylase hydrochloride 0.025 g, riboflavin 0.002 g, Lipoic acid. 0,012 g

Excipients: cocoa butter or solid fat to the weight of 0.95 g.

Packing

Cellular contoured packaging 5 suppositories. In a cardboard bundle 2 packs.

Mechanism of action

Korilip is a combined drug whose action is determined by the effects of its Vitamins and coenzymes, as well as their synergistic effect.

Cocarboxylase hydrochloride (coenzyme) catalyzes carboxylation and decarboxylation of a-keto acids, participates in carbohydrate metabolism, through participation in the pentose cycle indirectly contributes to the synthesis of nucleic acids, proteins, lipids.

Activates tissue metabolism. The drug is used for correction in metabolic acidosis, cell hypoxia, and other metabolic disorders, in case of insufficiency of the liver, kidney, cardiovascular system, chronic intoxication.

Riboflavin (vitamin B 2) as a coenzyme flavin proteins involved in the regulation of redox reactions, as well as in carbohydrate, protein and fat metabolism, plays an important role in the synthesis of hemoglobin and in maintaining the normal visual function of the eye, the state of the mucous membranes and skin.

Lipoic acid is involved in the oxidative decarboxylation of pyruvic acid and? -Ketoacids, in the regulation of lipid and carbohydrate metabolism, plays an important role in the process of energy formation in the body. Lipoic acid has a hepatoprotective effect, improves the detoxification function of the liver, protects against exposure to exo- and endotoxins.

Corilip improves tissue metabolism in various physiological and pathological conditions that require correction by cofactors and substrates.

Indications and usage

As an independent treatment or as an addition to the basic therapy for various pathological conditions in children, including:
- Chronic tissue hypoxia.
- Reduced immunity.
- Bacterial and viral infections.
- Chronic somatic diseases.
- Chronic intoxication.
- Conditions after severe illness.
- Eating disorders (malnutrition).

Contraindications

- Hypersensitivity reactions to the components that make up the drug.
- Inflammation or bleeding in the rectum (contraindication associated with the route of administration).

Dosage and administration

The drug is used rectally.

After releasing from the package, insert a suppository into the anus (after preliminary emptying of the intestines).
Children of early and preschool age (from 1 year to 6 years) - 1 suppository per day.
Children from 6 to 14 years old - 1-2 suppositories per day.

Duration of treatment is 10 days. The total duration of treatment is 3-4 courses with an interval of 20 days (3-4 months).

Adverse reactions

In rare cases, allergic reactions are possible: urticaria, pruritus, bronchospasm, dyspeptic phenomena.

If adverse reactions occur, stop taking the drug and consult a doctor.

Cautions

Along with the clinical condition, the criteria for the duration of treatment are cytochemical indicators of the activity of peripheral blood leukocyte enzymes (succinate dehydrogenase and glycerophosphate dehydrogenase).

Storage conditions

Store in a dark place at a temperature not higher than 9 ° C.

Corilip