ENDOFALK POWDER 55.318 G SACHET

Release form, composition and packaging

Powder for the preparation of oral solution white in color, crystalline, with a fragrant orange fruit flavor.

Excipients: colloidal silicon dioxide - 0.00046 g, fruit flavoring - 0.4 g, orange flavoring - 0.1 g, sodium saccharinate - 0.018 g

55.318 g - bags made of laminated material

pharmachologic effect

Laxative drug. The effect is due to the action of the ingredients contained in the preparation and is caused by diarrhea.

Macrogol 3350 (polyethylene glycol) due to the creation of an isosmolar solution prevents the absorption of water in the stomach and intestines, contributes to the accelerated passage and release of the contents of the gastrointestinal tract.

The electrolytes of the salts that make up the preparation prevent the violation of the body’s water-salt balance.

High molecular weight polyethylene glycol, due to lack of absorption and metabolism, prevents unwanted gas formation caused by the metabolizing action of bacteria.

Pharmacokinetics

High molecular weight polyethylene glycol is not absorbed in the gastrointestinal tract and is not metabolized during passage.

Indications

- preparation for endoscopic or x-ray examination of the lower intestine;

- preparation for surgical procedures, accompanied by the need for the absence of intestinal contents - chyme.

Dosing regimen

Adults and children over 18 years The drug is usually administered orally as a solution. Recommended dose: 3-4 liters of solution, taken in portions of 200-300 ml every 10 minutes.

To prepare 1 liter of solution, the contents of 2 sachets are dissolved in 0.5 l of cooled boiled (purified) water and then the volume of the solution is brought to 1 liter. In total, for complete bowel cleansing, it is recommended to prepare and take 3 liters of Endofalc solution. The time during which the solution should be taken is 3-4 hours.

The solution can be taken orally or it is administered through a nasogastric tube the night before or the morning of the day, the intended study or surgery on the intestine. Also on the evening before and on the morning of the study day, it is necessary to refrain from eating.

Side effect

From the digestive system: rarely - nausea, vomiting, flatulence, cramping pain; at the beginning and some time after taking it - a feeling of heaviness and discomfort in the abdomen.

From the side of the central nervous system: very rarely - sleep disturbance and general malaise.

Other: very rarely - allergic reactions.

Contraindications

- severe violations of the patient’s general condition (dehydration, cardiac and / or renal failure);

- intestinal obstruction;

- toxic expansion of the colon;

- gastric stenosis;

- perforation of the stomach or intestines;

- erosive and ulcerative lesions of the digestive tract;

- colitis, proceeding with high activity;

- violations of renal excretory function;

- children's age up to 18 years.

Use during pregnancy and lactation

There is still no experience with the clinical use of Endofalk in pregnant women. Therefore, Endofalc should be prescribed during pregnancy and lactation only under strict indications.

Application for violations of kidney function

Contraindicated in renal failure, impaired renal excretory function.

Use in children

Contraindicated in children and adolescents under 18 years of age.

Use in elderly patients

Elderly patients with existing comorbidities, the drug is recommended to be used under medical supervision.

special instructions

Elderly patients with existing comorbidities, the drug is recommended to be used under medical supervision.

The patient should inform the attending physician about all medications taken by him at the same time as Endofalc, as well as any side effects.

Influence on ability to drive motor transport and control mechanisms

Impact on the ability to drive vehicles and moving machinery is not revealed.

Overdose

Data on drug overdose due to the absence of such cases are not provided.

Drug interaction

The process of release of intestinal contents, caused by the action of the drug Endofalk, can lead to a violation of the absorption of simultaneously taken other drugs.

Terms and conditions of storage

The drug should be stored out of the reach of children, protected from light at a temperature not higher than 25 ° C. Shelf life - 5 years.

The prepared solution should be stored no more than 3 hours at a temperature of 25 ° C or 48 hours at a temperature of 5 ° C (in a refrigerator).

Pharmacy sales terms

The drug is approved for use as a means of OTC.